skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: A Mass Spectrometer in Every Fume Hood

Abstract

Since their inception, mass spectrometers have played a pivotal role in the direction and application of synthetic chemical research. The ability to develop new instrumentation to solve current analytical challenges in this area has always been at the heart of mass spectrometry, although progress has been slow at times. Herein, we briefly review the history of how mass spectrometry has been used to approach challenges in organic chemistry, how new developments in portable instrumentation and ambient ionization have been used to open novel areas of research, and how current techniques have the ability to expand on our knowledge of synthetic mechanisms and kinetics. Lastly, we discuss the relative paucity of work done in recent years to embrace the concept of improving benchtop synthetic chemistry with mass spectrometry, the disconnect between applications and fundamentals within these studies, and what hurdles still need to be overcome. .

Authors:
;  [1]
  1. University of North Texas, Department of Chemistry (United States)
Publication Date:
OSTI Identifier:
22776871
Resource Type:
Journal Article
Journal Name:
Journal of the American Society for Mass Spectrometry
Additional Journal Information:
Journal Volume: 29; Journal Issue: 8; Other Information: Copyright (c) 2018 American Society for Mass Spectrometry; http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 1044-0305
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; AEROSOLS; FUME HOODS; IONIZATION; MASS SPECTROMETERS; MASS SPECTROSCOPY; SYNTHESIS

Citation Formats

McBride, Ethan M., and Verbeck, Guido F., E-mail: gverbeck@unt.edu. A Mass Spectrometer in Every Fume Hood. United States: N. p., 2018. Web. doi:10.1007/S13361-018-1964-4.
McBride, Ethan M., & Verbeck, Guido F., E-mail: gverbeck@unt.edu. A Mass Spectrometer in Every Fume Hood. United States. doi:10.1007/S13361-018-1964-4.
McBride, Ethan M., and Verbeck, Guido F., E-mail: gverbeck@unt.edu. Wed . "A Mass Spectrometer in Every Fume Hood". United States. doi:10.1007/S13361-018-1964-4.
@article{osti_22776871,
title = {A Mass Spectrometer in Every Fume Hood},
author = {McBride, Ethan M. and Verbeck, Guido F., E-mail: gverbeck@unt.edu},
abstractNote = {Since their inception, mass spectrometers have played a pivotal role in the direction and application of synthetic chemical research. The ability to develop new instrumentation to solve current analytical challenges in this area has always been at the heart of mass spectrometry, although progress has been slow at times. Herein, we briefly review the history of how mass spectrometry has been used to approach challenges in organic chemistry, how new developments in portable instrumentation and ambient ionization have been used to open novel areas of research, and how current techniques have the ability to expand on our knowledge of synthetic mechanisms and kinetics. Lastly, we discuss the relative paucity of work done in recent years to embrace the concept of improving benchtop synthetic chemistry with mass spectrometry, the disconnect between applications and fundamentals within these studies, and what hurdles still need to be overcome. .},
doi = {10.1007/S13361-018-1964-4},
journal = {Journal of the American Society for Mass Spectrometry},
issn = {1044-0305},
number = 8,
volume = 29,
place = {United States},
year = {2018},
month = {8}
}