Magnetic Performance and Evaluation of Radiofrequency Hyperthermia of Perovskite La{sub 1−x}Sr{sub x}MnO{sub 3}

Journal Article · Sun Jul 15 00:00:00 EDT 2018 · Journal of Superconductivity and Novel Magnetism

DOI:https://doi.org/10.1007/S10948-017-4475-9· OSTI ID:22773968

Lotfi, Sheida; Bahari, Saeedeh; Bahari, Ali; Roudbari, Mandana ^[1]

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1. University of Mazandaran, Department of Solid State Physics (Iran, Islamic Republic of)

Magnetic nanoparticles (MNPs) can induce localized hyperthermia by alternating magnetic fields, in order to kill cells at tumor sites. In this study, La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles with x = 0.2, 0.3, 0.4, and 0.5 were prepared via sol–gel technique. The synthesized nanoparticles were characterized in terms of structure, morphology, and magnetic properties with Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and vibrating sample magnetometer (VSM) studies. The average size of nanoparticles was measured to be 57.09, 30.477, 10.24, and 35.982 nm by Williamson–Hall method for x = 0.2, 0.3, 0.4, and 0.5, respectively. The absence of hysteresis in the magnetic response of nanoparticles represents the superparamagnetic behavior. Toxicity test was also performed to evaluate the toxicity concerns of the prepared nanoparticles upon entrance to the body. Furthermore, the alternating current magnetic heating characteristics of La{sub 1−x}Sr{sub x}MnO{sub 3} nanoparticles was also studied, by 1 mg/mL concentration, to test the ability of the nanoparticles as magnetic hyperthermia treatment agents. The magnetothermia were measured in an RF magnetic field of 88 Oe and 430 kHz. The present work reveals that LSMO nanoparticles possess the biocompatible properties for biomedical applications and can provide the required heat at appropriate time.

• OSTI ID: 22773968
• Journal Information: Journal of Superconductivity and Novel Magnetism, Vol. 31, Issue 7; Other Information: Copyright (c) 2018 Springer Science+Business Media, LLC, part of Springer Nature; http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 1557-1939
• Country of Publication: United States
• Language: English

Related Subjects

75 CONDENSED MATTER PHYSICS
SUPERCONDUCTIVITY AND SUPERFLUIDITY
FOURIER TRANSFORM SPECTROMETERS
HEATING
HYPERTHERMIA
HYSTERESIS
INFRARED SPECTRA
LANTHANUM COMPOUNDS
MAGNETIC FIELDS
MAGNETIC PROPERTIES
MANGANATES
MANGANESE PHOSPHIDES
MORPHOLOGY
NANOPARTICLES
NEOPLASMS
PEROVSKITES
RADIOWAVE RADIATION
SCANNING ELECTRON MICROSCOPY
SOL-GEL PROCESS
SUPERPARAMAGNETISM
TOXICITY
TRANSMISSION ELECTRON MICROSCOPY
VIBRATING SAMPLE MAGNETOMETERS
X-RAY DIFFRACTION