Synthesis, Crystal Structure, Electrochemical Properties, and Biological Activity of 2-((1H-Benzimidazol-2-yl)methylamino)acetic Acid
- Jawaharlal Nehru Technological University Hyderabad, Department of Chemistry (India)
- University of Hyderabad, School of Chemistry (India)
A water soluble compound, (2-((1H-benzimidazol-2-yl)methylamino)acetic acid, BIGH, has been synthesized and structurally characterized by elemental analysis, IR and UV spectroscopies, {sup 1}H-NMR, thermogravimetric and differential thermal analyses, and single crystal and powder X-ray diffraction. BIGH can act as a flexible planar ligand with three potential coordination sites. It crystallizes in a monoclinic system with the sp. gr. P2{sub 1}/c with the unit cell parameters, a = 9.3764(7) Å, b = 11.5031(8) Å, c = 10.0543(6) Å, and Z = 4. The crystal structure was stabilized through inter-molecular hydrogen bonds. The anti-microbial activity of the compound has been studied against Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus, which showed a good activity against Bacillus subtilis. Cyclic voltammogram of the compound shows that it is a redox-active molecule.
- OSTI ID:
- 22758217
- Journal Information:
- Crystallography Reports, Vol. 63, Issue 4; Other Information: Copyright (c) 2018 Pleiades Publishing, Inc.; Country of input: International Atomic Energy Agency (IAEA); ISSN 1063-7745
- Country of Publication:
- United States
- Language:
- English
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ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
60 APPLIED LIFE SCIENCES
ACETIC ACID
BACILLUS SUBTILIS
DIFFERENTIAL THERMAL ANALYSIS
ELECTROCHEMISTRY
ESCHERICHIA COLI
HYDROGEN
HYDROGEN 1
LIGANDS
MOLECULES
MONOCLINIC LATTICES
MONOCRYSTALS
NUCLEAR MAGNETIC RESONANCE
POWDERS
PSEUDOMONAS
SPECTROSCOPY
STAPHYLOCOCCUS
SYNTHESIS
THERMAL GRAVIMETRIC ANALYSIS
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X-RAY DIFFRACTION