Prophylactic Temporary Occlusion of the Cystic Artery Using a Fibered Detachable Coil During {sup 90}Y Radioembolization

Journal Article · Sun Oct 15 04:00:00 EDT 2017 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-017-1688-Z· OSTI ID:22756393

Choi, Jin Woo ^[1]; Yoo, Min Young ^[2]; Kim, Hyo-Cheol ^[1]; Paeng, Jin Chul ^[3]; Kim, Yoon Jun ^[4]; Chung, Jin Wook ^[1]

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1. Seoul National University College of Medicine, Section of Interventional Radiology, Department of Radiology, Seoul National University Hospital (Korea, Republic of)
2. Chungbuk National University Hospital, Department of Nuclear Medicine (Korea, Republic of)
3. Seoul National University College of Medicine, Department of Nuclear Medicine, Seoul National University Hospital (Korea, Republic of)
4. Seoul National University College of Medicine, Department of Internal Medicine, Seoul National University Hospital (Korea, Republic of)

PurposeTo address the feasibility of prophylactic temporary occlusion of the cystic artery using a detachable coil during {sup 90}Y radioembolization.Materials and MethodsFrom January 2012 to October 2016, nine patients underwent temporary occlusion of the cystic artery during {sup 90}Y radioembolization. Based on the planning hepatic angiography, a detachable coil was deployed into the cystic artery, which arose from a more distal level (e.g., right anterior hepatic artery) than its usual origin, but the proximal 1 cm was left inside the microcatheter. {sup 90}Y microspheres were infused proximal to the cystic artery where the 99mTc-MAA had been infused, and then the coil was retrieved. Afterward, the patients underwent PET/CT imaging. Medical records were reviewed, and the differences in the uptake of 99mTc-MAA and {sup 90}Y microspheres in the gallbladder were evaluated using Wilcoxon’s signed-rank test.ResultsTemporary placement of a detachable coil was feasible in all cases. On the angiograms obtained after detachable coil placement, the distal cystic artery and gallbladder were partially identifiable in eight of the nine (88.8%) patients, but fully restored after the removal of the coils in all cases. The proportional uptake of 99mTc-MAA (mean, 4.35%) and {sup 90}Y (mean, 0.90%) in the gallbladder was significantly different due to the temporary occlusion of the cystic artery (p = 0.004). No clinical complications were identified for three months after the procedure.ConclusionTemporary occlusion of the cystic artery using a detachable coil appeared to be feasible and effective in reducing {sup 90}Y uptake in the gallbladder.

• OSTI ID: 22756393
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 10 Vol. 40; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BILIARY TRACT
BIOMEDICAL RADIOGRAPHY
MEDICAL RECORDS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOEMBOLIZATION
YTTRIUM 90