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Title: Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors

Abstract

Purpose: To assess intrafraction respiratory motion using a commercial kilovoltage imaging system for abdominal tumor patients with implanted fiducials and breathing constrained by pneumatic compression during stereotactic body radiation therapy (SBRT). Methods and Materials: A pneumatic compression belt limited respiratory motion in 19 patients with radiopaque fiducials in or near their tumor during SBRT for abdominal tumors. Kilovoltage images were acquired at 5- to 6-second intervals during treatment using a commercial system. Intrafractional fiducial displacements were measured using in-house software. The dosimetric effect of the observed displacements was calculated for 3 sessions for each patient. Results: Intrafraction displacement patterns varied between patients and between individual treatment sessions. Averaged over 19 patients, 73 sessions, 7.6% of craniocaudal displacements exceeded 0.5 cm, and 1.2% exceeded 0.75 cm. The calculated single-session dose to 95% of gross tumor volume differed from planned by an average of −1.2% (range, −11.1% to 4.8%) but only for 4 patients was the total 3-session calculated dose to 95% of gross tumor volume more than 3% different from planned. Conclusions: Our pneumatic compression limited intrafractional abdominal target motion, maintained target position established at setup, and was moderately effective in preserving coverage. Commercially available intrafractional imaging is useful for surveillance but can bemore » made more effective and reliable.« less

Authors:
 [1];  [2];  [3]; ; ; ; ;  [1];  [4]
  1. Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York (United States)
  2. Department of Radiation Oncology, China-Japan Friendship Hospital, Beijing (China)
  3. Department of Radiotherapy, Henan Provincial People's Hospital, Zhengzhou (China)
  4. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York (United States)
Publication Date:
OSTI Identifier:
22648718
Resource Type:
Journal Article
Resource Relation:
Journal Name: International Journal of Radiation Oncology, Biology and Physics; Journal Volume: 95; Journal Issue: 3; Other Information: Copyright (c) 2015 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; COMPRESSION; COMPUTER CODES; IMAGES; NEOPLASMS; PATIENTS; PNEUMATICS; RADIOTHERAPY

Citation Formats

Yorke, Ellen, E-mail: yorke@mskcc.org, Xiong, Ying, Han, Qian, Zhang, Pengpeng, Mageras, Gikas, Lovelock, Michael, Pham, Hai, Xiong, Jian-Ping, and Goodman, Karyn A.. Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors. United States: N. p., 2016. Web. doi:10.1016/J.IJROBP.2015.11.018.
Yorke, Ellen, E-mail: yorke@mskcc.org, Xiong, Ying, Han, Qian, Zhang, Pengpeng, Mageras, Gikas, Lovelock, Michael, Pham, Hai, Xiong, Jian-Ping, & Goodman, Karyn A.. Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors. United States. doi:10.1016/J.IJROBP.2015.11.018.
Yorke, Ellen, E-mail: yorke@mskcc.org, Xiong, Ying, Han, Qian, Zhang, Pengpeng, Mageras, Gikas, Lovelock, Michael, Pham, Hai, Xiong, Jian-Ping, and Goodman, Karyn A.. Fri . "Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors". United States. doi:10.1016/J.IJROBP.2015.11.018.
@article{osti_22648718,
title = {Kilovoltage Imaging of Implanted Fiducials to Monitor Intrafraction Motion With Abdominal Compression During Stereotactic Body Radiation Therapy for Gastrointestinal Tumors},
author = {Yorke, Ellen, E-mail: yorke@mskcc.org and Xiong, Ying and Han, Qian and Zhang, Pengpeng and Mageras, Gikas and Lovelock, Michael and Pham, Hai and Xiong, Jian-Ping and Goodman, Karyn A.},
abstractNote = {Purpose: To assess intrafraction respiratory motion using a commercial kilovoltage imaging system for abdominal tumor patients with implanted fiducials and breathing constrained by pneumatic compression during stereotactic body radiation therapy (SBRT). Methods and Materials: A pneumatic compression belt limited respiratory motion in 19 patients with radiopaque fiducials in or near their tumor during SBRT for abdominal tumors. Kilovoltage images were acquired at 5- to 6-second intervals during treatment using a commercial system. Intrafractional fiducial displacements were measured using in-house software. The dosimetric effect of the observed displacements was calculated for 3 sessions for each patient. Results: Intrafraction displacement patterns varied between patients and between individual treatment sessions. Averaged over 19 patients, 73 sessions, 7.6% of craniocaudal displacements exceeded 0.5 cm, and 1.2% exceeded 0.75 cm. The calculated single-session dose to 95% of gross tumor volume differed from planned by an average of −1.2% (range, −11.1% to 4.8%) but only for 4 patients was the total 3-session calculated dose to 95% of gross tumor volume more than 3% different from planned. Conclusions: Our pneumatic compression limited intrafractional abdominal target motion, maintained target position established at setup, and was moderately effective in preserving coverage. Commercially available intrafractional imaging is useful for surveillance but can be made more effective and reliable.},
doi = {10.1016/J.IJROBP.2015.11.018},
journal = {International Journal of Radiation Oncology, Biology and Physics},
number = 3,
volume = 95,
place = {United States},
year = {Fri Jul 01 00:00:00 EDT 2016},
month = {Fri Jul 01 00:00:00 EDT 2016}
}