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Title: Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience

Abstract

PurposeTo evaluate the safety and diagnostic ability of percutaneous needle biopsy performed immediately after lung radiofrequency ablation (RFA).Materials and MethodsFrom May 2013 to April 2014, percutaneous needle biopsy was performed immediately after RFA for 3 patients (2 men and 1 woman, aged 57–76 years) who had lung tumors measuring 1.3–2.6 cm in diameter. All patients had prior history of malignancy, and all tumors were radiologically diagnosed as malignant. Obtained specimens were pathologically classified using standard hematoxylin and eosin staining.ResultsWe completed three planned sessions of RFA followed by percutaneous needle biopsy, all of which obtained tumor tissue that could be pathologically diagnosed. Two tumors were metastatic from renal clear cell carcinoma and rectal adenocarcinoma, respectively; one tumor was primary lung adenocarcinoma. There was no death or major complication related to the procedures. Although pneumothorax occurred in two patients, these resolved without the need for aspiration or chest tube placement. Tumor seeding was not observed, but 21 months after the procedure, one case developed local tumor progression that was treated by additional RFA.ConclusionPathologic diagnosis was possible by needle biopsy immediately after RFA for lung tumors. This technique may reduce the risks and efforts of performing biopsy and RFA on separate occasions.

Authors:
 [1];  [2]; ; ; ; ; ;  [1]; ;  [3];  [2]
  1. Aichi Cancer Center Hospital, Department of Diagnostic and Interventional Radiology (Japan)
  2. Aichi Cancer Center Hospital, Department of Pathology and Molecular Diagnosis (Japan)
  3. Aichi Cancer Center Hospital, Department of Thoracic Surgery (Japan)
Publication Date:
OSTI Identifier:
22645490
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 39; Journal Issue: 8; Other Information: Copyright (c) 2016 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ABLATION; ANIMAL TISSUES; BIOPSY; CARCINOMAS; CHEST; DEATH; DIAGNOSIS; ELDERLY PEOPLE; EOSIN; HAZARDS; HEMATOXYLIN; KIDNEYS; LUNGS; METASTASES; PATIENTS; RADIOWAVE RADIATION; RECTUM; SAFETY

Citation Formats

Hasegawa, Takaaki, E-mail: t-hasegawa@aichi-cc.jp, Kondo, Chiaki, Sato, Yozo, Inaba, Yoshitaka, Yamaura, Hidekazu, Kato, Mina, Murata, Shinichi, Onoda, Yui, Kuroda, Hiroaki, Sakao, Yukinori, and Yatabe, Yasushi. Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience. United States: N. p., 2016. Web. doi:10.1007/S00270-016-1324-3.
Hasegawa, Takaaki, E-mail: t-hasegawa@aichi-cc.jp, Kondo, Chiaki, Sato, Yozo, Inaba, Yoshitaka, Yamaura, Hidekazu, Kato, Mina, Murata, Shinichi, Onoda, Yui, Kuroda, Hiroaki, Sakao, Yukinori, & Yatabe, Yasushi. Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience. United States. doi:10.1007/S00270-016-1324-3.
Hasegawa, Takaaki, E-mail: t-hasegawa@aichi-cc.jp, Kondo, Chiaki, Sato, Yozo, Inaba, Yoshitaka, Yamaura, Hidekazu, Kato, Mina, Murata, Shinichi, Onoda, Yui, Kuroda, Hiroaki, Sakao, Yukinori, and Yatabe, Yasushi. Mon . "Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience". United States. doi:10.1007/S00270-016-1324-3.
@article{osti_22645490,
title = {Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience},
author = {Hasegawa, Takaaki, E-mail: t-hasegawa@aichi-cc.jp and Kondo, Chiaki and Sato, Yozo and Inaba, Yoshitaka and Yamaura, Hidekazu and Kato, Mina and Murata, Shinichi and Onoda, Yui and Kuroda, Hiroaki and Sakao, Yukinori and Yatabe, Yasushi},
abstractNote = {PurposeTo evaluate the safety and diagnostic ability of percutaneous needle biopsy performed immediately after lung radiofrequency ablation (RFA).Materials and MethodsFrom May 2013 to April 2014, percutaneous needle biopsy was performed immediately after RFA for 3 patients (2 men and 1 woman, aged 57–76 years) who had lung tumors measuring 1.3–2.6 cm in diameter. All patients had prior history of malignancy, and all tumors were radiologically diagnosed as malignant. Obtained specimens were pathologically classified using standard hematoxylin and eosin staining.ResultsWe completed three planned sessions of RFA followed by percutaneous needle biopsy, all of which obtained tumor tissue that could be pathologically diagnosed. Two tumors were metastatic from renal clear cell carcinoma and rectal adenocarcinoma, respectively; one tumor was primary lung adenocarcinoma. There was no death or major complication related to the procedures. Although pneumothorax occurred in two patients, these resolved without the need for aspiration or chest tube placement. Tumor seeding was not observed, but 21 months after the procedure, one case developed local tumor progression that was treated by additional RFA.ConclusionPathologic diagnosis was possible by needle biopsy immediately after RFA for lung tumors. This technique may reduce the risks and efforts of performing biopsy and RFA on separate occasions.},
doi = {10.1007/S00270-016-1324-3},
journal = {Cardiovascular and Interventional Radiology},
number = 8,
volume = 39,
place = {United States},
year = {Mon Aug 15 00:00:00 EDT 2016},
month = {Mon Aug 15 00:00:00 EDT 2016}
}