Diagnostic Ability of Percutaneous Needle Biopsy Immediately After Radiofrequency Ablation for Malignant Lung Tumors: An Initial Experience

Journal Article · Mon Aug 15 04:00:00 EDT 2016 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-016-1324-3· OSTI ID:22645490

Hasegawa, Takaaki ^[1]; Kondo, Chiaki ^[2]; Sato, Yozo; Inaba, Yoshitaka; Yamaura, Hidekazu; Kato, Mina; Murata, Shinichi; Onoda, Yui ^[1]; Kuroda, Hiroaki; Sakao, Yukinori ^[3]; Yatabe, Yasushi ^[2]

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1. Aichi Cancer Center Hospital, Department of Diagnostic and Interventional Radiology (Japan)
2. Aichi Cancer Center Hospital, Department of Pathology and Molecular Diagnosis (Japan)
3. Aichi Cancer Center Hospital, Department of Thoracic Surgery (Japan)

PurposeTo evaluate the safety and diagnostic ability of percutaneous needle biopsy performed immediately after lung radiofrequency ablation (RFA).Materials and MethodsFrom May 2013 to April 2014, percutaneous needle biopsy was performed immediately after RFA for 3 patients (2 men and 1 woman, aged 57–76 years) who had lung tumors measuring 1.3–2.6 cm in diameter. All patients had prior history of malignancy, and all tumors were radiologically diagnosed as malignant. Obtained specimens were pathologically classified using standard hematoxylin and eosin staining.ResultsWe completed three planned sessions of RFA followed by percutaneous needle biopsy, all of which obtained tumor tissue that could be pathologically diagnosed. Two tumors were metastatic from renal clear cell carcinoma and rectal adenocarcinoma, respectively; one tumor was primary lung adenocarcinoma. There was no death or major complication related to the procedures. Although pneumothorax occurred in two patients, these resolved without the need for aspiration or chest tube placement. Tumor seeding was not observed, but 21 months after the procedure, one case developed local tumor progression that was treated by additional RFA.ConclusionPathologic diagnosis was possible by needle biopsy immediately after RFA for lung tumors. This technique may reduce the risks and efforts of performing biopsy and RFA on separate occasions.

• OSTI ID: 22645490
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 8 Vol. 39; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ABLATION
ANIMAL TISSUES
BIOPSY
CARCINOMAS
CHEST
DEATH
DIAGNOSIS
ELDERLY PEOPLE
EOSIN
HAZARDS
HEMATOXYLIN
KIDNEYS
LUNGS
METASTASES
PATIENTS
RADIOWAVE RADIATION
RECTUM
SAFETY