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Title: Prostatic Arterial Embolization Treating Moderate-to-Severe Lower Urinary Tract Symptoms Related to Benign Prostate Hyperplasia: A Meta-Analysis

Abstract

PurposeTo evaluate the clinical efficiency and safety of PAE treating moderate-to-severe LUTS related to BPH.Materials and MethodsA systematic literature search was performed using PUBMED, EMBASE, Cochrane database of systematic review, and Web of Science, up to April 2016, to identify eligible studies. The Cochrane Collaboration’s RevMan 5.3 was used to analyze the extracted data. Random- or fixed-effect model was selected to fit the pooled out heterogeneity.Results20 eligible studies were included in this meta-analysis. Synthetic data showed that there were statistically significant improvements in IPSS (MD = −13.25; 95% CI −14.81 to −11.69; P < 0.00001), QoL score (MD = −2.34; 95% CI −2.69 to −2.00, P < 0.00001), PSA level (MD = −1.33; 95% CI −1.86 to −0.80; P < 0.00001), PV (MD = −28.00; 95% CI −35.94 to −20.07; P < 0.00001), Qmax (MD = 5.51; 95% CI 4.62 to 6.40; P < 0.00001), and PVR (MD = −67.8; 95% CI −81.35 to −53.60; P < 0.00001). There was no significant difference in IIEF score (MD = 0.93; 95% CI 0.43–1.42; P = 0.07). Major complications following PAE include pain in the perineum, retropubic area, and/or urethra (9.4%), and hematuria (9.0%).ConclusionsPAE should be considered to be the very promising alternative treatment for those who do not want or cannot tolerate surgical treatment, with its benefits on IPSS, QoL score, PSA level, PV, Qmax, and PVR without affectingmore » erectile function.« less

Authors:
 [1];  [2];  [3];  [1];  [4]; ;  [1]
  1. Sichuan University, Institute of Urology (Laboratory of Reconstructive Urology) (China)
  2. Guizhou Provincial People’s Hospital, Department of Urology Surgery (China)
  3. Guizhou Provincial People’s Hospital, Department of Cardiology (China)
  4. The First Affiliated Hospital of Guangzhou Medical University, Department of Urology, Minimally Invasive Surgery Center (China)
Publication Date:
OSTI Identifier:
22645348
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 40; Journal Issue: 1; Conference: BSIR 2016: Britisch Society of Interventional Radiology 2016 annual meeting, Manchester (United Kingdom), 15-17 Nov 2016; Other Information: Copyright (c) 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BPH; PAIN; PHOSPHORUS 40; PHOSPHORUS 42; PONDS; PROSTATE; RANDOMNESS; REVIEWS; SAFETY; SURGERY; URINARY TRACT; VASCULAR DISEASES

Citation Formats

Feng, Shijian, Tian, Ye, Liu, Wei, Li, Zirui, Deng, Tuo, Li, Hong, and Wang, Kunjie, E-mail: wangkj@scu.edu.cn. Prostatic Arterial Embolization Treating Moderate-to-Severe Lower Urinary Tract Symptoms Related to Benign Prostate Hyperplasia: A Meta-Analysis. United States: N. p., 2017. Web. doi:10.1007/S00270-016-1516-X.
Feng, Shijian, Tian, Ye, Liu, Wei, Li, Zirui, Deng, Tuo, Li, Hong, & Wang, Kunjie, E-mail: wangkj@scu.edu.cn. Prostatic Arterial Embolization Treating Moderate-to-Severe Lower Urinary Tract Symptoms Related to Benign Prostate Hyperplasia: A Meta-Analysis. United States. doi:10.1007/S00270-016-1516-X.
Feng, Shijian, Tian, Ye, Liu, Wei, Li, Zirui, Deng, Tuo, Li, Hong, and Wang, Kunjie, E-mail: wangkj@scu.edu.cn. Sun . "Prostatic Arterial Embolization Treating Moderate-to-Severe Lower Urinary Tract Symptoms Related to Benign Prostate Hyperplasia: A Meta-Analysis". United States. doi:10.1007/S00270-016-1516-X.
@article{osti_22645348,
title = {Prostatic Arterial Embolization Treating Moderate-to-Severe Lower Urinary Tract Symptoms Related to Benign Prostate Hyperplasia: A Meta-Analysis},
author = {Feng, Shijian and Tian, Ye and Liu, Wei and Li, Zirui and Deng, Tuo and Li, Hong and Wang, Kunjie, E-mail: wangkj@scu.edu.cn},
abstractNote = {PurposeTo evaluate the clinical efficiency and safety of PAE treating moderate-to-severe LUTS related to BPH.Materials and MethodsA systematic literature search was performed using PUBMED, EMBASE, Cochrane database of systematic review, and Web of Science, up to April 2016, to identify eligible studies. The Cochrane Collaboration’s RevMan 5.3 was used to analyze the extracted data. Random- or fixed-effect model was selected to fit the pooled out heterogeneity.Results20 eligible studies were included in this meta-analysis. Synthetic data showed that there were statistically significant improvements in IPSS (MD = −13.25; 95% CI −14.81 to −11.69; P < 0.00001), QoL score (MD = −2.34; 95% CI −2.69 to −2.00, P < 0.00001), PSA level (MD = −1.33; 95% CI −1.86 to −0.80; P < 0.00001), PV (MD = −28.00; 95% CI −35.94 to −20.07; P < 0.00001), Qmax (MD = 5.51; 95% CI 4.62 to 6.40; P < 0.00001), and PVR (MD = −67.8; 95% CI −81.35 to −53.60; P < 0.00001). There was no significant difference in IIEF score (MD = 0.93; 95% CI 0.43–1.42; P = 0.07). Major complications following PAE include pain in the perineum, retropubic area, and/or urethra (9.4%), and hematuria (9.0%).ConclusionsPAE should be considered to be the very promising alternative treatment for those who do not want or cannot tolerate surgical treatment, with its benefits on IPSS, QoL score, PSA level, PV, Qmax, and PVR without affecting erectile function.},
doi = {10.1007/S00270-016-1516-X},
journal = {Cardiovascular and Interventional Radiology},
number = 1,
volume = 40,
place = {United States},
year = {Sun Jan 15 00:00:00 EST 2017},
month = {Sun Jan 15 00:00:00 EST 2017}
}