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Title: Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques

Abstract

PurposeTo compare recurrence of lower urinary tract symptoms (LUTS) recurrence at 12 months following original prostate artery embolization (oPAE) or “proximal embolization first, then embolize distal” (PErFecTED) PAE for benign prostatic hyperplasia (BPH).Materials and Methods105 consecutive patients older than 45 years, with prostate size greater than 30 cm{sup 3}, International Prostate Symptom Score (IPSS) ≥ 8, quality of life (QoL) index ≥ 3, and refractory status or intolerance of medical management were prospectively enrolled between June 2008 and August 2013. The study was IRB-approved, and all patients provided informed consent. Patients underwent oPAE or PErFecTED PAE and were followed for at least 12 months. Technical success was defined as bilateral embolization and clinical success (non-recurrence) was defined as removal of the Foley catheter in patients with urinary retention, IPSS < 8 and QoL index < 3 at 12 months of follow-up. Nonparametric statistics were used to compare the study groups due to the size of the study population and distributions of clinical data.Results97 patients had 12-month data and were categorized as oPAE without recurrence (n = 46), oPAE with recurrence (n  = 13), PErFecTED without recurrence (n  = 36), or PErFecTED with recurrence (n  = 2). Recurrence was significantly more common in oPAE patients (χ{sup 2}, p = 0.026). Unilateral embolization was significantly associated with recurrence among patients who underwentmore » oPAE (χ{sup 2}, p = 0.032).ConclusionsBoth oPAE and PErFecTED PAE are safe and effective methods for treatment of LUTS, but PErFecTED PAE is associated with a significantly lower rate of symptom recurrence.« less

Authors:
;  [1];  [2];  [3];  [1];  [4];  [1];  [4]
  1. University of Sao Paulo, Department of Radiology (Brazil)
  2. The Dartmouth Institute for Health Policy and Clinical Practice (United States)
  3. University of Miami Medical Center, Department of Interventional Radiology (United States)
  4. University of Sao Paulo, Department of Urology (Brazil)
Publication Date:
OSTI Identifier:
22645295
Resource Type:
Journal Article
Resource Relation:
Journal Name: Cardiovascular and Interventional Radiology; Journal Volume: 40; Journal Issue: 3; Other Information: Copyright (c) 2017 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); http://www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA)
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTERIES; COMPARATIVE EVALUATIONS; INDEXES; NITROGEN 13; PATIENTS; PROSTATE; SYMPTOMS; URINARY TRACT; VASCULAR DISEASES

Citation Formats

Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br, Moreira, Airton Mota, Harward, Sardis Honoria, Bhatia, Shivank, Assis, Andre Moreira de, Srougi, Miguel, Cerri, Giovanni Guido, and Antunes, Alberto Azoubel. Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques. United States: N. p., 2017. Web. doi:10.1007/S00270-017-1569-5.
Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br, Moreira, Airton Mota, Harward, Sardis Honoria, Bhatia, Shivank, Assis, Andre Moreira de, Srougi, Miguel, Cerri, Giovanni Guido, & Antunes, Alberto Azoubel. Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques. United States. doi:10.1007/S00270-017-1569-5.
Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br, Moreira, Airton Mota, Harward, Sardis Honoria, Bhatia, Shivank, Assis, Andre Moreira de, Srougi, Miguel, Cerri, Giovanni Guido, and Antunes, Alberto Azoubel. Wed . "Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques". United States. doi:10.1007/S00270-017-1569-5.
@article{osti_22645295,
title = {Recurrence of Lower Urinary Tract Symptoms Following Prostate Artery Embolization for Benign Hyperplasia: Single Center Experience Comparing Two Techniques},
author = {Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br and Moreira, Airton Mota and Harward, Sardis Honoria and Bhatia, Shivank and Assis, Andre Moreira de and Srougi, Miguel and Cerri, Giovanni Guido and Antunes, Alberto Azoubel},
abstractNote = {PurposeTo compare recurrence of lower urinary tract symptoms (LUTS) recurrence at 12 months following original prostate artery embolization (oPAE) or “proximal embolization first, then embolize distal” (PErFecTED) PAE for benign prostatic hyperplasia (BPH).Materials and Methods105 consecutive patients older than 45 years, with prostate size greater than 30 cm{sup 3}, International Prostate Symptom Score (IPSS) ≥ 8, quality of life (QoL) index ≥ 3, and refractory status or intolerance of medical management were prospectively enrolled between June 2008 and August 2013. The study was IRB-approved, and all patients provided informed consent. Patients underwent oPAE or PErFecTED PAE and were followed for at least 12 months. Technical success was defined as bilateral embolization and clinical success (non-recurrence) was defined as removal of the Foley catheter in patients with urinary retention, IPSS < 8 and QoL index < 3 at 12 months of follow-up. Nonparametric statistics were used to compare the study groups due to the size of the study population and distributions of clinical data.Results97 patients had 12-month data and were categorized as oPAE without recurrence (n = 46), oPAE with recurrence (n  = 13), PErFecTED without recurrence (n  = 36), or PErFecTED with recurrence (n  = 2). Recurrence was significantly more common in oPAE patients (χ{sup 2}, p = 0.026). Unilateral embolization was significantly associated with recurrence among patients who underwent oPAE (χ{sup 2}, p = 0.032).ConclusionsBoth oPAE and PErFecTED PAE are safe and effective methods for treatment of LUTS, but PErFecTED PAE is associated with a significantly lower rate of symptom recurrence.},
doi = {10.1007/S00270-017-1569-5},
journal = {Cardiovascular and Interventional Radiology},
number = 3,
volume = 40,
place = {United States},
year = {Wed Mar 15 00:00:00 EDT 2017},
month = {Wed Mar 15 00:00:00 EDT 2017}
}