Noninvasive micromanipulation of live HIV-1 infected cells via laser light

Journal Article · Thu Dec 31 00:00:00 EST 2015 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4937641· OSTI ID:22494409

Mthunzi, Patience ^[1]

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1. National Laser Centre, Council for Scientific and Industrial Research, Pretoria (South Africa)

Live mammalian cells from various tissues of origin can be aseptically and noninvasively micromanipulated via lasers of different regimes. Laser-driven techniques are therefore paving a path toward the advancement of human immuno-deficiency virus (HIV-1) investigations. Studies aimed at the interaction of laser light, nanomaterials, and biological materials can also lead to an understanding of a wealth of disease conditions and result in photonics-based therapies and diagnostic tools. Thus, in our research, both continuous wave and pulsed lasers operated at varying wavelengths are employed, as they possess special properties that allow classical biomedical applications. This paper discusses photo-translocation of antiretroviral drugs into HIV-1 permissive cells and preliminary results of low-level laser therapy (LLLT) in HIV-1 infected cells.

• OSTI ID: 22494409
• Journal Information: AIP Conference Proceedings, Vol. 1697, Issue 1; Conference: 5. IUPAP international conference on women in physics, Waterloo (Canada), 5-8 Aug 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
63 RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS
AIDS VIRUS
ANIMAL TISSUES
BIOLOGICAL MATERIALS
DIAGNOSTIC TECHNIQUES
DRUGS
HUMAN POPULATIONS
LASER RADIATION
LASERS
NANOMATERIALS
THERAPY
WAVELENGTHS