Impact of plasma jet vacuum ultraviolet radiation on reactive oxygen species generation in bio-relevant liquids

Journal Article · Mon Dec 14 23:00:00 EST 2015 · Physics of Plasmas

DOI:https://doi.org/10.1063/1.4934989· OSTI ID:22489906

Jablonowski, H.; Hammer, M. U.; Reuter, S. ^[1]; Bussiahn, R.; Weltmann, K. -D.; Woedtke, Th. von ^[2]

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1. Center for Innovation Competence plasmatis, Felix-Hausdorff-Str. 2, 17489 Greifswald (Germany)
2. Leibniz Institute for Plasma Science and Technology, INP Greifswald e.V. Felix-Hausdorff-Str. 2, 17489 Greifswald (Germany)

Plasma medicine utilizes the combined interaction of plasma produced reactive components. These are reactive atoms, molecules, ions, metastable species, and radiation. Here, ultraviolet (UV, 100–400 nm) and, in particular, vacuum ultraviolet (VUV, 10–200 nm) radiation generated by an atmospheric pressure argon plasma jet were investigated regarding plasma emission, absorption in a humidified atmosphere and in solutions relevant for plasma medicine. The energy absorption was obtained for simple solutions like distilled water (dH{sub 2}O) or ultrapure water and sodium chloride (NaCl) solution as well as for more complex ones, for example, Rosewell Park Memorial Institute (RPMI 1640) cell culture media. As moderate stable reactive oxygen species, hydrogen peroxide (H{sub 2}O{sub 2}) was studied. Highly reactive oxygen radicals, namely, superoxide anion (O{sub 2}{sup •−}) and hydroxyl radicals ({sup •}OH), were investigated by the use of electron paramagnetic resonance spectroscopy. All species amounts were detected for three different treatment cases: Plasma jet generated VUV and UV radiation, plasma jet generated UV radiation without VUV part, and complete plasma jet including all reactive components additionally to VUV and UV radiation. It was found that a considerable amount of radicals are generated by the plasma generated photoemission. From the experiments, estimation on the low hazard potential of plasma generated VUV radiation is discussed.

• OSTI ID: 22489906
• Journal Information: Physics of Plasmas, Journal Name: Physics of Plasmas Journal Issue: 12 Vol. 22; ISSN PHPAEN; ISSN 1070-664X
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
70 PLASMA PHYSICS AND FUSION TECHNOLOGY
ANIONS
ARGON
ATMOSPHERIC PRESSURE
CELL CULTURES
ELECTRON SPIN RESONANCE
ENERGY ABSORPTION
FAR ULTRAVIOLET RADIATION
HYDROGEN PEROXIDE
HYDROXYL RADICALS
MEDICINE
OXYGEN
PHOTOEMISSION
PLASMA JETS
SODIUM CHLORIDES
SPECTROSCOPY
WATER