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Title: Gas-phase study on uridine: Conformation and X-ray photofragmentation

Abstract

Fragmentation of RNA nucleoside uridine, induced by carbon 1s core ionization, has been studied. The measurements by combined electron and ion spectroscopy have been performed in gas phase utilizing synchrotron radiation. As uridine is a combination of d-ribose and uracil, which have been studied earlier with the same method, this study also considers the effect of chemical environment and the relevant functional groups. Furthermore, since in core ionization the initial core hole is always highly localized, charge migration prior to fragmentation has been studied here. This study also demonstrates the destructive nature of core ionization as in most cases the C 1s ionization of uridine leads to concerted explosions producing only small fragments with masses ≤43 amu. In addition to fragmentation patterns, we found out that upon evaporation the sugar part of the uridine molecule attains hexagonal form.

Authors:
; ;  [1];  [2];  [1];  [3];  [1];  [4]
  1. Department of Physics and Astronomy, University of Turku, FIN-20014 Turku (Finland)
  2. Royal Institute of Technology KTH, Physics department, S-10691 Stockholm (Sweden)
  3. (Spain)
  4. (MatSurf), FIN-20014 Turku (Finland)
Publication Date:
OSTI Identifier:
22415797
Resource Type:
Journal Article
Journal Name:
Journal of Chemical Physics
Additional Journal Information:
Journal Volume: 142; Journal Issue: 19; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0021-9606
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; CARBON; ELECTRON SPECTROSCOPY; ELECTRONS; EVAPORATION; HOLES; ION SPECTROSCOPY; IONIZATION; MASS; MOLECULES; PHASE STUDIES; RIBOSE; RNA; SACCHAROSE; SYNCHROTRON RADIATION; URIDINE; X RADIATION

Citation Formats

Itälä, Eero, E-mail: ersita@utu.fi, Kooser, Kuno, Levola, Helena, Rachlew, Elisabeth, Ha, Dang Trinh, Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid, Kukk, Edwin, and Turku University Centre for Materials and Surfaces. Gas-phase study on uridine: Conformation and X-ray photofragmentation. United States: N. p., 2015. Web. doi:10.1063/1.4919878.
Itälä, Eero, E-mail: ersita@utu.fi, Kooser, Kuno, Levola, Helena, Rachlew, Elisabeth, Ha, Dang Trinh, Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid, Kukk, Edwin, & Turku University Centre for Materials and Surfaces. Gas-phase study on uridine: Conformation and X-ray photofragmentation. United States. doi:10.1063/1.4919878.
Itälä, Eero, E-mail: ersita@utu.fi, Kooser, Kuno, Levola, Helena, Rachlew, Elisabeth, Ha, Dang Trinh, Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid, Kukk, Edwin, and Turku University Centre for Materials and Surfaces. Thu . "Gas-phase study on uridine: Conformation and X-ray photofragmentation". United States. doi:10.1063/1.4919878.
@article{osti_22415797,
title = {Gas-phase study on uridine: Conformation and X-ray photofragmentation},
author = {Itälä, Eero, E-mail: ersita@utu.fi and Kooser, Kuno and Levola, Helena and Rachlew, Elisabeth and Ha, Dang Trinh and Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid and Kukk, Edwin and Turku University Centre for Materials and Surfaces},
abstractNote = {Fragmentation of RNA nucleoside uridine, induced by carbon 1s core ionization, has been studied. The measurements by combined electron and ion spectroscopy have been performed in gas phase utilizing synchrotron radiation. As uridine is a combination of d-ribose and uracil, which have been studied earlier with the same method, this study also considers the effect of chemical environment and the relevant functional groups. Furthermore, since in core ionization the initial core hole is always highly localized, charge migration prior to fragmentation has been studied here. This study also demonstrates the destructive nature of core ionization as in most cases the C 1s ionization of uridine leads to concerted explosions producing only small fragments with masses ≤43 amu. In addition to fragmentation patterns, we found out that upon evaporation the sugar part of the uridine molecule attains hexagonal form.},
doi = {10.1063/1.4919878},
journal = {Journal of Chemical Physics},
issn = {0021-9606},
number = 19,
volume = 142,
place = {United States},
year = {2015},
month = {5}
}