Line broadening interference for high-resolution nuclear magnetic resonance spectra under inhomogeneous magnetic fields

Journal Article · Tue Apr 07 04:00:00 EDT 2015 · Journal of Chemical Physics

DOI:https://doi.org/10.1063/1.4916520· OSTI ID:22415604

Wei, Zhiliang; Yang, Jian; Lin, Yanqin; Chen, Zhong ^[1]; Chen, Youhe ^[2]

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1. Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, State Key Laboratory of Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen 361005 (China)
2. Department of Electronic Engineering, Xiamen University, Xiamen 361005 (China)

Nuclear magnetic resonance spectroscopy serves as an important tool for analyzing chemicals and biological metabolites. However, its performance is subject to the magnetic-field homogeneity. Under inhomogeneous fields, peaks are broadened to overlap each other, introducing difficulties for assignments. Here, we propose a method termed as line broadening interference (LBI) to provide high-resolution information under inhomogeneous magnetic fields by employing certain gradients in the indirect dimension to interfere the magnetic-field inhomogeneity. The conventional spectral-line broadening is thus interfered to be non-diagonal, avoiding the overlapping among adjacent resonances. Furthermore, an inhomogeneity correction algorithm is developed based on pattern recognition to recover the high-resolution information from LBI spectra. Theoretical deductions are performed to offer systematic and detailed analyses on the proposed method. Moreover, experiments are conducted to prove the feasibility of the proposed method for yielding high-resolution spectra in inhomogeneous magnetic fields.

• OSTI ID: 22415604
• Journal Information: Journal of Chemical Physics, Journal Name: Journal of Chemical Physics Journal Issue: 13 Vol. 142; ISSN JCPSA6; ISSN 0021-9606
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
ABSORPTION SPECTROSCOPY
ALGORITHMS
CORRECTIONS
INHOMOGENEOUS FIELDS
INTERFERENCE
LINE BROADENING
MAGNETIC FIELDS
METABOLITES
NMR SPECTRA
NUCLEAR MAGNETIC RESONANCE
PATTERN RECOGNITION
RESOLUTION