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Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets

Journal Article · · Journal of Chemical Physics
DOI:https://doi.org/10.1063/1.4914902· OSTI ID:22415535
; ;  [1]
  1. Department of Physics and Astronomy, University of Southern California, Los Angeles, California 90089-0484 (United States)
We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through an N–H ⋅ ⋅ ⋅ N hydrogen bond leads to a proton transfer from the indole group of tryptophan to the imidazole group of histidine in a radical cationic environment.
OSTI ID:
22415535
Journal Information:
Journal of Chemical Physics, Journal Name: Journal of Chemical Physics Journal Issue: 11 Vol. 142; ISSN JCPSA6; ISSN 0021-9606
Country of Publication:
United States
Language:
English

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