Rapid and noncontact photoacoustic tomography imaging system using an interferometer with high-speed phase modulation technique

Journal Article · Wed Apr 15 00:00:00 EDT 2015 · Review of Scientific Instruments

DOI:https://doi.org/10.1063/1.4918801· OSTI ID:22392471

Liu, Jun ^[1]; Tang, Zhilie; Wu, Yongbo ^[1]; Wang, Yi ^[2]

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1. School of Physics and Telecom Engineering, South China Normal University, Guangzhou 510006 (China)
2. School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004 (China)

We designed, fabricated, and tested a rapid and noncontact photoacoustic tomography (PAT) imaging system using a low-coherence interferometer with high-speed phase modulation technique. Such a rapid and noncontact probing system can greatly decrease the time of imaging. The proposed PAT imaging system is experimentally verified by capturing images of a simulated tissue sample and the blood vessels within the ear flap of a mouse (pinna) in vivo. The axial and lateral resolutions of the system are evaluated at 45 and ∼15 μm, respectively. The imaging depth of the system is 1 mm in a special phantom. Our results show that the proposed system opens a promising way to realize noncontact, real-time PAT.

• OSTI ID: 22392471
• Journal Information: Review of Scientific Instruments, Vol. 86, Issue 4; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0034-6748
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
ANIMAL TISSUES
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BLOOD VESSELS
IN VIVO
INTERFEROMETERS
MICE
MODULATION
PHANTOMS
RESOLUTION
SIMULATION
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