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Multi-particle trapping and manipulation by a high-frequency array transducer

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.4902923· OSTI ID:22392085
; ; ;  [1]
  1. NIH Resource Center for Medical Ultrasonic Transducer Technology and Department of Biomedical Engineering, University of Southern California, Los Angeles, California 90089 (United States)

We report the multiple micro-particle trapping and manipulation by a single-beam acoustic tweezer using a high-frequency array transducer. A single acoustic beam generated by a 30 MHz ultrasonic linear array transducer can entrap and transport multiple micro-particles located at the main lobe and the grating lobes. The distance between trapped particles can be adjusted by changing the transmit arrangement of array-based acoustic tweezers and subsequently the location of grating lobes. The experiment results showed that the proposed method can trap and manipulate multiple particles within a range of hundreds of micrometers. Due to its simplicity and low acoustic power, which is critical to protect cells from any thermal and mechanical damages, the technique may be used for transportation of cells in cell biology, biosensors, and tissue engineering.

OSTI ID:
22392085
Journal Information:
Applied Physics Letters, Journal Name: Applied Physics Letters Journal Issue: 21 Vol. 105; ISSN APPLAB; ISSN 0003-6951
Country of Publication:
United States
Language:
English

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