A comparison of HDR near source dosimetry using a treatment planning system, Monte Carlo simulation, and radiochromic film

Journal Article · Mon Jul 01 04:00:00 EDT 2013 · Medical Dosimetry

DOI:https://doi.org/10.1016/J.MEDDOS.2012.10.006· OSTI ID:22262807

Amoush, Ahmad ^[1]; Luckstead, Marcus; Lamba, Michael; Elson, Howard; Kassing, William ^[1]

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1. Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH (United States)

This study aimed to investigate the high-dose rate Iridium-192 brachytherapy, including near source dosimetry, of a catheter-based applicator from 0.5 mm to 1 cm along the transverse axis. Radiochromic film and Monte Carlo (MC) simulation were used to generate absolute dose for the catheter-based applicator. Results from radiochromic film and MC simulation were compared directly to the treatment planning system (TPS) based on the American Association of Physicists in Medicine Updated Task Group 43 (TG-43U1) dose calculation formalism. The difference between dose measured using radiochromic film along the transverse plane at 0.5 mm from the surface and the predicted dose by the TPS was 24%±13%. The dose difference between the MC simulation along the transverse plane at 0.5 mm from the surface and the predicted dose by the TPS was 22.1%±3%. For distances from 1.5 mm to 1 cm from the surface, radiochromic film and MC simulation agreed with TPS within an uncertainty of 3%. The TPS under-predicts the dose at the surface of the applicator, i.e., 0.5 mm from the catheter surface, as compared to the measured and MC simulation predicted dose. MC simulation results demonstrated that 15% of this error is due to neglecting the beta particles and discrete electrons emanating from the sources and not considered by the TPS, and 7% of the difference was due to the photon alone, potentially due to the differences in MC dose modeling, photon spectrum, scoring techniques, and effect of the presence of the catheter and the air gap. Beyond 1 mm from the surface, the TPS dose algorithm agrees with the experimental and MC data within 3%.

• OSTI ID: 22262807
• Journal Information: Medical Dosimetry, Journal Name: Medical Dosimetry Journal Issue: 2 Vol. 38; ISSN 0958-3947
• Country of Publication: United States
• Language: English

Related Subjects

61 RADIATION PROTECTION AND DOSIMETRY
BETA PARTICLES
BRACHYTHERAPY
COMPUTERIZED SIMULATION
FILM DOSIMETRY
IRIDIUM 192
MONTE CARLO METHOD
PLANNING