Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers

Journal Article · Sun Jul 01 04:00:00 EDT 2012 · Medical Dosimetry

DOI:https://doi.org/10.1016/J.MEDDOS.2011.08.002· OSTI ID:22130408

Camingue, Pamela; Christian, Rochelle; Ng, Davin ^[1]; Williams, Preston ^[1]; Amin, Mayankkumar; Roniger, Dominique L. ^[1]

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1. University of Texas M.D. Anderson Cancer Center, School of Health Professions, Houston, TX (United States)

The purpose of this study was to compare 4 different external beam radiation therapy treatment techniques for the treatment of T1-2, N0, M0 glottic cancers: traditional lateral beams with wedges (3D), 5-field intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), and proton therapy. Treatment plans in each technique were created for 10 patients using consistent planning parameters. The photon treatment plans were optimized using Philips Pinnacle{sub 3} v.9 and the IMRT and VMAT plans used the Direct Machine Parameter Optimization algorithm. The proton treatment plans were optimized using Varian Eclipse Proton v.8.9. The prescription used for each plan was 63 Gy in 28 fractions. The contours for spinal cord, right carotid artery, left carotid artery, and normal tissue were created with respect to the patient's bony anatomy so that proper comparisons of doses could be made with respect to volume. An example of the different isodose distributions will be shown. The data collection for comparison purposes includes: clinical treatment volume coverage, dose to spinal cord, dose to carotid arteries, and dose to normal tissue. Data comparisons will be displayed graphically showing the maximum, mean, median, and ranges of doses.

• OSTI ID: 22130408
• Journal Information: Medical Dosimetry, Journal Name: Medical Dosimetry Journal Issue: 2 Vol. 37; ISSN 0958-3947
• Country of Publication: United States
• Language: English

Related Subjects

61 RADIATION PROTECTION AND DOSIMETRY
ALGORITHMS
BEAMS
CAROTID ARTERIES
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DOSIMETRY
NEOPLASMS
OPTIMIZATION
PATIENTS
PHOTONS
PLANNING
PROTONS
RADIATION DOSES
RADIOTHERAPY
SPINAL CORD