Radioembolization of the Spleen: A Revisited Approach for the Treatment of Malignant Lymphomatous Splenomegaly
- Jules Bordet Institute, ULB, Department of Nuclear Medicine (Belgium)
- Jules Bordet Institute, ULB, Department of Haematology (Belgium)
- Jules Bordet Institute, ULB, Department of Anatomo-Pathology (Belgium)
- UMC Sint-Pieter, Department of Interventional Radiology (Belgium)
- Jules Bordet Institute, ULB, Department of Radiophysics (Belgium)
- Jules Bordet Institute, ULB, Department of Radiotherapy (Belgium)
- Jules Bordet Institute, ULB, Department of Radiology (Belgium)
Intraarterial administration of {sup 90}Y microspheres to the spleen in patients with malignant lymphoma was mentioned once in the literature in 1973. This case study illustrates the potential indication of selective internal radiotherapy in a heavily pretreated patient with highly refractory disease with a marginal zone lymphoma in leukemic phase and symptomatic splenomegaly. We describe the clinical course of disease; the biological and clinical response to the treatment after radioembolization; and simulation and dosimetry by multimodal imaging via single-photon emission computed tomography and computed tomography. The advantages of radioembolization for the management of lymphomatous splenomegaly are discussed.
- OSTI ID:
- 22121751
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 36, Issue 4; Other Information: Copyright (c) 2013 Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Article Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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