On the use of HDR {sup 60}Co source with the MammoSite Radiation Therapy System
- Department of Medical Physics and Engineering, Strahlenklinik, Klinikum Offenbach GmbH, 63069 Offenbach am Main, Germany and Nuclear and Particle Physics Section, Physics Department, University of Athens, Panepistimioupolis, Ilisia, 157 71 Athens (Greece)
This work summarizes Monte Carlo results in order to evaluate the potential of using HDR {sup 60}Co sources in accelerated partial breast irradiation (APBI) with the MammoSite applicator. Simulations have been performed using the MCNP5 Monte Carlo Code, in simple geometries comprised of two concentric spheres; the internal consisting of selected concentrations, C, of a radiographic contrast solution in water (Omnipaque 300) to simulate the MammoSite balloon and the external consisting of water to simulate surrounding tissue. The magnitude of the perturbation of delivered dose due to the radiographic contrast medium used in the MammoSite applicator is calculated. At the very close vicinity of the balloon surface, a dose build-up region is observed, which leads to a dose overestimation by the treatment planning system (TPS) which depends on Omnipaque 300 solution concentration (and is in order of 2.3%, 3.0%, and 4.5%, respectively, at 1 mm away from the balloon - water interface, for C=10%, 15%, and 20%). However, dose overestimation by the TPS is minimal for points lying at the prescription distance (d=1 cm) or beyond, for all simulated concentrations and radii of MammoSite balloon. An analytical estimation of the integral dose outside the CTV in the simple geometries simulated shows that dose to the breast for MammoSite applications is expected to be comparable using HDR {sup 60}Co and {sup 192}Ir sources, and higher than that for {sup 169}Yb. The higher enegies of {sup 60}Co sources result to approximately twice radiation protection requirements as compared to {sup 169}Ir sources. However, they allow for more accurate dosimetry calculation with currently used treatment planning algorithms for {sup 60}Co sources, compared to {sup 169}Ir.
- OSTI ID:
- 22095268
- Journal Information:
- Medical Physics, Journal Name: Medical Physics Journal Issue: 12 Vol. 35; ISSN 0094-2405; ISSN MPHYA6
- Country of Publication:
- United States
- Language:
- English
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