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Title: Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy

Abstract

The case of a patient diagnosed with uterine cervix cancer is presented as an example of the clinical application of the radiobiological compensation method implemented at Centro Estatal de Cancerologia de Durango. Radiotherapy treatment was initially modified to compensate for the chemotherapy component and, as medical complications arose during treatment delivery resulting in an 18 days gap, new compensation followed. All physical and radiobiological assumptions to calculate the Biologically Effective Dose in the external beam and brachytherapy parts of the treatment are presented. Good local control of the tumor was achieved, the theoretical tolerance limits for the organs at risk were not surpassed and the patient manifested no extensive morbidity.

Authors:
; ;  [1];  [2]
  1. Centro Estatal de Cancerologia de Durango, Victoria de Durango, Durango (Mexico)
  2. (Mexico)
Publication Date:
OSTI Identifier:
22075685
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1494; Journal Issue: 1; Conference: 12. Mexican symposium on medical physics, Oaxaca (Mexico), 16-19 Mar 2012; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 61 RADIATION PROTECTION AND DOSIMETRY; BRACHYTHERAPY; CHEMOTHERAPY; CONTROL; DISEASE INCIDENCE; DOSIMETRY; GYNECOLOGY; HAZARDS; NEOPLASMS; PATIENTS; RADIATION DOSES; TOLERANCE

Citation Formats

Herrera, Higmar, Yanez, Elvia, Lopez, Jesus, and ISSSTE General Hospital Dr. Santiago Ramon y Cajal, Victoria de Durango, Durango. Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy. United States: N. p., 2012. Web. doi:10.1063/1.4764590.
Herrera, Higmar, Yanez, Elvia, Lopez, Jesus, & ISSSTE General Hospital Dr. Santiago Ramon y Cajal, Victoria de Durango, Durango. Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy. United States. doi:10.1063/1.4764590.
Herrera, Higmar, Yanez, Elvia, Lopez, Jesus, and ISSSTE General Hospital Dr. Santiago Ramon y Cajal, Victoria de Durango, Durango. Tue . "Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy". United States. doi:10.1063/1.4764590.
@article{osti_22075685,
title = {Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy},
author = {Herrera, Higmar and Yanez, Elvia and Lopez, Jesus and ISSSTE General Hospital Dr. Santiago Ramon y Cajal, Victoria de Durango, Durango},
abstractNote = {The case of a patient diagnosed with uterine cervix cancer is presented as an example of the clinical application of the radiobiological compensation method implemented at Centro Estatal de Cancerologia de Durango. Radiotherapy treatment was initially modified to compensate for the chemotherapy component and, as medical complications arose during treatment delivery resulting in an 18 days gap, new compensation followed. All physical and radiobiological assumptions to calculate the Biologically Effective Dose in the external beam and brachytherapy parts of the treatment are presented. Good local control of the tumor was achieved, the theoretical tolerance limits for the organs at risk were not surpassed and the patient manifested no extensive morbidity.},
doi = {10.1063/1.4764590},
journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1494,
place = {United States},
year = {2012},
month = {10}
}