Survival After Accidental Extrahepatic Distribution of Y90 Microspheres to the Mesentery During a Radioembolization Procedure

Journal Article · Wed Aug 15 00:00:00 EDT 2012 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-011-0286-8· OSTI ID:22066581

Sabet, Amir; Ahmadzadehfar, Hojjat ^[1]; Schaefer, Nico ^[2]; Wilhelm, Kai; Schueller, Heinrich ^[3]; Ezziddin, Samer ^[1]

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1. University Hospital, Department of Nuclear Medicine (Germany)
2. University Hospital, Department of Surgery (Germany)
3. University Hospital, Department of Radiology, Division of Radiation Oncology (Germany)

We present the acute management and outcome of a patient after an accidental mesenteric distribution of Y90 microspheres during radioembolization (RE). This report describes and highlights: (1) the incidence of a significant reflux during a RE session while injecting into a replaced right hepatic artery from the superior mesenteric artery, (2) the appearance of diffuse mesenteric Y90 distribution in bremsstrahlung-imaging, (3) the management protocol with the radiation protection agent amifostine, (4) the development of typical adverse effects in the expected time window, and (5) survival of the patient without long-term sequelae. This report should sensitize physicians to this particular problem and may help to avoid as well as manage similar radioembolization incidences.

• OSTI ID: 22066581
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 35, Issue 4; Other Information: Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BREMSSTRAHLUNG
LIVER
MESENTERY
MICROSPHERES
PATIENTS
RADIATION PROTECTION
YTTRIUM 90