Modeling and Analysis Support for Acceleratro-based Production of Mo-99

Technical Report · Fri Sep 01 04:00:00 EDT 2023

DOI:https://doi.org/10.2172/2203704· OSTI ID:2203704

Strons, Phil ^[1]; Patapenka, Andrei ^[1]; Chemerisov, Sergey ^[1]

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1. Argonne National Laboratory (ANL), Argonne, IL (United States)

NorthStar Medical Radioisotopes, LLC, is in the process of commissioning a medical isotope production facility, which will use high-power electron accelerators to produce molybdenum-99 (Mo-99), the parent of technetium-99m (Tc-99m), through photonuclear reactions in molybdenum-100 (Mo-100). In this approach, a target comprising multiple thin disks of enriched molybdenum metal is bombarded with a 40-MeV electron beam. Electrons that impinge on the molybdenum target produce bremsstrahlung x-rays that cause the nuclear reaction. Because enriched Mo-100 is expensive, there is a desire to use as much beam power as possible to achieve maximum production yield and minimize the size of the target. This requirement leads to very high beam power density (heat deposition in the target), which creates challenging requirements for target cooling. In the latest concept developed by NorthStar, a stack of target (sintered molybdenum) disks is irradiated from two sides by a 40-MeV electron beam, with a total power of 250 kW (125 kW from each side). The target disks are cooled by pressurized helium gas flowing through channels between the disks. Inconel windows in the target housing form a pressure boundary between the helium within the housing and the evacuated beam tube.

• Research Organization: Argonne National Laboratory (ANL), Argonne, IL (United States)
• Sponsoring Organization: USDOE National Nuclear Security Administration (NNSA), Office of Defense Nuclear Nonproliferation. Office of Material Management and Minimization (M3)
• DOE Contract Number: AC02-06CH11357
• OSTI ID: 2203704
• Report Number(s): ANL--23/54; 185546
• Country of Publication: United States
• Language: English

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