Covered Biodegradable Stent: New Therapeutic Option for the Management of Esophageal Perforation or Anastomotic Leak

Journal Article · Thu Dec 15 04:00:00 EST 2011 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-010-0059-9· OSTI ID:21608645

Cerna, Marie; Koecher, Martin; Valek, Vlastimil ^[1]; Aujesky, Rene; Neoral, Cestmir ^[2]; Andrasina, Tomas; Panek, Jiri; Mahathmakanthi, Shankari ^[1]

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1. University Hospital, Department of Radiology (Czech Republic)
2. University Hospital, Department of Surgery (Czech Republic)

Purpose: This study was designed to evaluate our experience with the treatment of postoperative anastomotic leaks and benign esophageal perforations with covered biodegradable stents. Materials and Methods: From 2008 to 2010, we treated five men with either an anastomotic leak or benign esophageal perforation by implanting of covered biodegradable Ella-BD stents. The average age of the patients was 60 (range, 38-74) years. Postoperative anastomotic leaks were treated in four patients (1 after esophagectomy, 1 after resection of diverticulum, 2 after gastrectomy). In one patient, perforation occurred as a complication of the treatment of an esophageal rupture (which occurred during a balloon dilatation of benign stenosis) with a metallic stent. Results: Seven covered biodegradable stents were implanted in five patients. Primary technical success was 100%. Clinical success (leak sealing) was achieved in four of the five patients (80%). Stent migration occurred in three patients. In two of these patients, the leak had been sealed by the time of stent migration, therefore no reintervention was necessary. In one patient an additional stent had to be implanted. Conclusion: The use of biodegradable covered stents for the treatment of anastomotic leaks or esophageal perforations is technically feasible and safe. The initial results are promising; however, larger number of patients will be required to evaluate the capability of these biodegradable stents in the future. The use of biodegradable material for coverage of the stent is essential.

• OSTI ID: 21608645
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 6 Vol. 34; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BODY
DIGESTIVE SYSTEM
ESOPHAGUS
FAILURES
GASTRECTOMY
MALES
MAMMALS
MAN
MATERIALS
MEDICINE
MEN
ORGANS
PATIENTS
PERFORATION
PRIMATES
RUPTURES
SURGERY
THERAPY
VERTEBRATES