Endovascular Treatment of Acute Arterial Hemorrhage in Trauma Patients Using Ethylene Vinyl Alcohol Copolymer (Onyx)

Journal Article · Wed Feb 15 00:00:00 EST 2012 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-011-0134-X· OSTI ID:21608627

Mueller-Wille, R; Heiss, P ^[1]; Herold, T ^[2]; Rennert, J; Hoffstetter, P; Stroszczynski, C ^[1]; Zorger, N ^[3]

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1. University Medical Center Regensburg, Department of Radiology (Germany)
2. Helios Klinikum Berlin-Buch, Department of Radiology (Germany)
3. Krankenhaus Barmherzige Brueder Regensburg, Department of Radiology (Germany)

Purpose: This study was designed to determine the feasibility and efficacy of endovascular embolization with liquid embolic agent ethylene vinyl alcohol copolymer (Onyx) in patients with acute traumatic arterial bleeding. Methods: This is a retrospective review of 13 patients (9 men and 4 women; mean age 45 years) with severe trauma who underwent embolotherapy using Onyx from November 2003 to February 2009. Bleeding was located in the pelvis (5 patients), kidney (3 patients), mesenteric region (2 patients), retroperitoneal space (2 patients), neck (1 patient), and thigh (1 patient). In three cases (23.1%), Onyx was used in conjunction with coils. We evaluate the technical and clinical success, procedural and embolization time, occurrence of rebleeding, and embolotherapy-related complications, such as necrosis or migration of Onyx into nontarget vessels. Results: In all patients, embolotherapy was technically and clinically successful on the first attempt. Control of bleeding could be reached with a mean time of 19 (range, 4-63) min after correct placement of the microcatheter in the feeding artery. No recurrent bleeding was detected. No unintended necrosis or migration of Onyx into a nontarget region was observed. During the follow-up period, three patients (23.1%) died due to severe intracranial hemorrhage, cardiac arrest, and sepsis. Conclusions: Transcatheter embolization with new liquid embolic agent Onyx is technically feasible and effective in trauma patients with acute arterial hemorrhage.

• OSTI ID: 21608627
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 35, Issue 1; Other Information: DOI: 10.1007/s00270-011-0134-x; Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ALCOHOLS
ARTERIES
CONTROL
COPOLYMERS
ETHYLENE
HEMORRHAGE
INJURIES
KIDNEYS
LIQUIDS
MEN
NECK
NECROSIS
PATIENTS
PELVIS
WOMEN
ALKENES
ANIMALS
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
DISEASES
FEMALES
FLUIDS
HYDROCARBONS
HYDROXY COMPOUNDS
MALES
MAMMALS
MAN
ORGANIC COMPOUNDS
ORGANIC POLYMERS
ORGANS
PATHOLOGICAL CHANGES
POLYMERS
PRIMATES
SYMPTOMS
VERTEBRATES