Results of a Seven-Year, Single-Centre Experience of the Long-Term Outcomes of Bovine Ureter Grafts Used as Novel Conduits for Haemodialysis Fistulas

Journal Article · Sat Oct 15 04:00:00 EDT 2011 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-011-0096-Z· OSTI ID:21608578

Das, Neelan; Bratby, Mark J; Shrivastava, Vivek ^[1]; Cornall, Alison J ^[2]; Darby, Christopher R ^[3]; Boardman, Philip ^[4]; Anthony, Susan; Uberoi, Raman ^[1]

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1. John Radcliffe Hospital, Department of Interventional Radiology (United Kingdom)
2. Churchill Hospital, Department of Nephrology (United Kingdom)
3. Churchill Hospital, Department of Vascular Surgery (United Kingdom)
4. Churchill Hospital, Department of Interventional Radiology (United Kingdom)

Purpose: To report the long-term outcomes of bovine ureter grafts as novel conduits for haemodialysis fistulas. Materials and Methods: Thirty-five patients underwent placement of a total of 40 SynerGraft 100 (SG100; CryoLife Europa{sup Registered-Sign}, Guildford, UK) bovine ureter grafts between April 2002 and February 2009. Prospective data were collected on all patients, including active surveillance with blood flow studies and 6-monthly duplex ultrasound studies. Main outcome measures were primary and secondary patency rates. Results: Mean follow-up time was 97 weeks (range 4-270). Thirteen patients died from unrelated causes during the study period; 12 of these patients had a functioning graft at the time of death. Five patients underwent transplantation, and all had a functioning graft at transplantation. Twelve patients had a functioning graft at the end of the study period. One hundred and ten stenoses were detected, and 97 venoplasty procedures were performed. Of the stenoses, 41.8% were located at the venous anastomosis, 12.7% within the graft, 17.3% in the outflow veins, and 28.1% in central veins. No arterial stenoses were detected. Primary patency rates were 53% at 6 months and 14% at 1 year. Secondary patency rates were 81% at 6 months, 75% at 1 year, and 56% at 2 years. Conclusions: Active surveillance and intervention was able to achieve satisfactory long-term secondary patency for these novel conduits compared with those made of PTFE seen in other studies.

• OSTI ID: 21608578
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 5 Vol. 34; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BLOOD FLOW
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CATTLE
DEATH
DOMESTIC ANIMALS
FLUORINATED ALIPHATIC HYDROCARBONS
GRAFTS
HALOGENATED ALIPHATIC HYDROCARBONS
MAMMALS
MATERIALS
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC POLYMERS
ORGANS
PATIENTS
PETROCHEMICALS
PETROLEUM PRODUCTS
PLASTICS
POLYETHYLENES
POLYMERS
POLYOLEFINS
POLYTETRAFLUOROETHYLENE
RUMINANTS
SYNTHETIC MATERIALS
TEFLON
TRANSPLANTS
URETERS
URINARY TRACT
VEINS
VERTEBRATES