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Title: Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations

Abstract

Introduction: Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses. Methods: Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D real-time fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluated according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations. Results: Median tumor size was 2.6 (range, 1.0-14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was <2.5 cm. One patient developed a minor complication. Median follow-up was 16.0 (range, 6.4-19.8) months. Conclusions: 3D real-time fluoroscopy cone beam CT-guided biopsy of renal masses is feasible and safe. However, these first results suggest that diagnostic accuracy may be limited inmore » patients with renal masses <2.5 cm.« less

Authors:
 [1]; ;  [2];  [3]
  1. University Medical Center Utrecht, Department of Urology (Netherlands)
  2. University Medical Center Utrecht, Department of Radiology (Netherlands)
  3. University Medical Center Utrecht, Department of Pathology (Netherlands)
Publication Date:
OSTI Identifier:
21608520
Resource Type:
Journal Article
Journal Name:
Cardiovascular and Interventional Radiology
Additional Journal Information:
Journal Volume: 35; Journal Issue: 3; Other Information: DOI: 10.1007/s00270-011-0237-4; Copyright (c) 2012 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE); Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0174-1551
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ACCURACY; BIOPSY; DIAGNOSIS; EVALUATION; EXPLORATION; FLUOROSCOPY; IMAGES; KIDNEYS; NEOPLASMS; PATIENTS; RECOMMENDATIONS; SAFETY; SOLIDS; BIOMEDICAL RADIOGRAPHY; BODY; DIAGNOSTIC TECHNIQUES; DISEASES; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY

Citation Formats

Kroeze, Stephanie G. C., Huisman, Merel, Verkooijen, Helena M, Diest, Paul J. van, Ruud Bosch, J. L. H., and Bosch, Maurice A. A. J. van den, E-mail: mbosch@umcutrecht.nl. Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations. United States: N. p., 2012. Web. doi:10.1007/S00270-011-0237-4.
Kroeze, Stephanie G. C., Huisman, Merel, Verkooijen, Helena M, Diest, Paul J. van, Ruud Bosch, J. L. H., & Bosch, Maurice A. A. J. van den, E-mail: mbosch@umcutrecht.nl. Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations. United States. doi:10.1007/S00270-011-0237-4.
Kroeze, Stephanie G. C., Huisman, Merel, Verkooijen, Helena M, Diest, Paul J. van, Ruud Bosch, J. L. H., and Bosch, Maurice A. A. J. van den, E-mail: mbosch@umcutrecht.nl. Fri . "Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations". United States. doi:10.1007/S00270-011-0237-4.
@article{osti_21608520,
title = {Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations},
author = {Kroeze, Stephanie G. C. and Huisman, Merel and Verkooijen, Helena M and Diest, Paul J. van and Ruud Bosch, J. L. H. and Bosch, Maurice A. A. J. van den, E-mail: mbosch@umcutrecht.nl},
abstractNote = {Introduction: Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses. Methods: Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D real-time fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluated according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations. Results: Median tumor size was 2.6 (range, 1.0-14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was <2.5 cm. One patient developed a minor complication. Median follow-up was 16.0 (range, 6.4-19.8) months. Conclusions: 3D real-time fluoroscopy cone beam CT-guided biopsy of renal masses is feasible and safe. However, these first results suggest that diagnostic accuracy may be limited in patients with renal masses <2.5 cm.},
doi = {10.1007/S00270-011-0237-4},
journal = {Cardiovascular and Interventional Radiology},
issn = {0174-1551},
number = 3,
volume = 35,
place = {United States},
year = {2012},
month = {6}
}