Coherent diffraction of a single virus particle: The impact of a water layer on the available orientational information

Journal Article · Tue Mar 15 04:00:00 EDT 2011 · Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics (Print)

DOI:https://doi.org/10.1103/PHYSREVE.83.031907· OSTI ID:21560071

Wang, F; Weckert, E; Ziaja, B; Larsson, D S. D.; Spoel, D van der ^[1]

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1. HASYLAB, Deutsches Elektronen-Synchrotron, Notkestrasse 85, D-22607 Hamburg (Germany)

Coherent diffractive imaging using x-ray free-electron lasers (XFELs) may provide a unique opportunity for high-resolution structural analysis of single particles sprayed from an aqueous solution into the laser beam. As a result, diffraction images are measured from randomly oriented objects covered by a water layer. We analyze theoretically how the thickness of the covering water layer influences the structural and orientational information contained in the recorded diffraction images. This study has implications for planned experiments on single-particle imaging with XFELs.

• OSTI ID: 21560071
• Journal Information: Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics (Print), Journal Name: Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics (Print) Journal Issue: 3 Vol. 83; ISSN 1539-3755
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
62 RADIOLOGY AND NUCLEAR MEDICINE
AQUEOUS SOLUTIONS
BEAMS
COHERENT SCATTERING
DIFFRACTION
DIMENSIONS
DISPERSIONS
ELECTROMAGNETIC RADIATION
FREE ELECTRON LASERS
HOMOGENEOUS MIXTURES
HYDROGEN COMPOUNDS
IMAGES
IONIZING RADIATIONS
LASERS
LAYERS
MICROORGANISMS
MIXTURES
OXYGEN COMPOUNDS
PARASITES
PARTICLES
PHOTON BEAMS
RADIATIONS
RESOLUTION
SCATTERING
SOLUTIONS
THICKNESS
VIRUSES
WATER
X RADIATION