Auger electron spectroscopy for the determination of sex and age related Ca/P ratio at different bone sites
- Department of Medical Physics, Medical School, University of Ioannina, Ioannina 45110 (Greece)
The Ca/P ratio of normal cortical and trabecular rat bone was measured by Auger electron spectroscopy (AES). Semiquantitative analysis was carried out using ratio techniques to draw conclusions on how age, sex and bone site affect the relative composition of calcium and phosphorus. Results show that Ca/P ratio is not sex dependent; quite the opposite, bone sites exhibit variations in elemental stoichiometry where femoral sections demonstrate higher Ca/P ratio than rear and front tibias. Age-related changes are more distinct for cortical bone in comparison with the trabecular bone. The latter's Ca/P ratio remains unaffected from all the parameters under study. This study confirms that AES is able to successfully quantify bone mineral main elements when certain critical points, related to the experimental conditions, are addressed effectively.
- OSTI ID:
- 21519881
- Journal Information:
- Journal of Applied Physics, Vol. 108, Issue 7; Other Information: DOI: 10.1063/1.3490118; (c) 2010 American Institute of Physics; ISSN 0021-8979
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
AUGER ELECTRON SPECTROSCOPY
CALCIUM
CHEMICAL ANALYSIS
COMPARATIVE EVALUATIONS
MINERALS
PHOSPHORUS
RATS
SEX DEPENDENCE
TIBIA
TRABECULAR BONE
ALKALINE EARTH METALS
ANIMAL TISSUES
ANIMALS
BODY
BONE TISSUES
CONNECTIVE TISSUE
ELECTRON SPECTROSCOPY
ELEMENTS
EVALUATION
MAMMALS
METALS
NONMETALS
ORGANS
RODENTS
SKELETON
SPECTROSCOPY
VERTEBRATES