Four-Dimensional Measurement of the Displacement of Internal Fiducial Markers During 320-Multislice Computed Tomography Scanning of Thoracic Esophageal Cancer

Journal Article · Tue Feb 01 00:00:00 EST 2011 · International Journal of Radiation Oncology, Biology and Physics

DOI:https://doi.org/10.1016/j.ijrobp.2010.03.045· OSTI ID:21491597

Yamashita, Hideomi; Kida, Satoshi; Sakumi, Akira; Haga, Akihiro; Ito, Saori; Onoe, Tsuyoshi; Okuma, Kae; Ino, Kenji; Akahane, Masaaki; Ohtomo, Kuni ^[1]; Nakagawa, Keiichi ^[1]

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1. Department of Radiology, University of Tokyo Hospital, Tokyo (Japan)

Purpose: To investigate the three-dimensional movement of internal fiducial markers placed near esophageal cancers using 320-multislice CT. Methods and Materials: This study examined 22 metal markers in the esophageal wall near the primary tumors of 12 patients treated with external-beam photon radiotherapy. Motion assessment was analyzed in 41 respiratory phases during 20 s of cine CT in the radiotherapy position. Results: Motion in the cranial-caudal (CC) direction showed a strong correlation (R{sup 2} > 0.4) with the respiratory curve in most markers (73%). The average absolute amplitude of the marker movement was 1.5 {+-} 1.6 mm, 1.6 {+-} 1.7 mm, and 3.3 {+-} 3.3 mm in the left-right (LR), anterior-posterior (AP), and CC directions, respectively. The average marker displacements in the CC direction between peak exhalation and inhalation for the 22 clips were 1.1 mm (maximum, 5.5 mm), 3.0 mm (14.5 mm), and 5.1 mm (16.3 mm) for the upper, middle, and lower thoracic esophagus, respectively. Conclusions: Motion in primary esophagus tumor was evaluated with 320-multislice CT. According to this study, 4.3 mm CC, 1.5 mm AP, and 2.0 mm LR in the upper, 7.4 mm CC, 3.0 mm AP, and 2.4 mm LR in the middle, and 13.8 mm CC, 6.6 mm AP, and 6.8 mm LR in the lower thoracic esophagus provided coverage of tumor motion in 95% of the cases in our study population.

• OSTI ID: 21491597
• Journal Information: International Journal of Radiation Oncology, Biology and Physics, Vol. 79, Issue 2; Other Information: DOI: 10.1016/j.ijrobp.2010.03.045; PII: S0360-3016(10)00595-X; Copyright (c) 2011 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
COMPUTERIZED TOMOGRAPHY
ESOPHAGUS
EXHALATION
FOUR-DIMENSIONAL CALCULATIONS
INHALATION
MOTION
NEOPLASMS
PHOTONS
RADIOTHERAPY
RESPIRATION
BODY
BOSONS
CLEARANCE
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
ELEMENTARY PARTICLES
EXCRETION
INTAKE
MASSLESS PARTICLES
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
THERAPY
TOMOGRAPHY