Clinical Evaluation of an Immbolization System for Stereotactic Body Radiotherapy Using Helical Tomotherapy
- Department of Radiation Oncology, School of Medicine, Cancer Therapy and Research Center, University of Texas Health Science Center-San Antonio, San Antonio, TX (United States)
In this study, a clinical evaluation of the Body Pro-Lok{sup TM} System combined with the TomoTherapy megavoltage computed tomography (MVCT) was performed for lung and liver stereotactic body radiotherapy (SBRT) to reduce interfractional setup uncertainty. Twenty patients treated with 3-5 fractions of SBRT were analyzed retrospectively. The Body Pro-Lok{sup TM} system was used in both CT simulation and during patient treatment setup. Patients were immobilized with a vacuum cushion placed posteriorly over the thoracic region, an abdominal compression plate, and a knee and foot sponge. Pretreatment MVCT scans of the TomoTherapy HI-ART II unit were fused with the planning kVCT before delivery of each fraction to determine the interfractional setup error. A total of 84 shifts were analyzed to assess the interfractional setup accuracy. Results showed that the mean interfractional setup errors and standard deviations were -0.9 {+-} 3.1 mm, 1.2 {+-} 5.5 mm, and 6.5 {+-} 2.6 mm for lateral (IEC-X), longitudinal (IEC-Y), and vertical (IEC-Z) variations, respectively. The maximum motion was 17.1 mm in the longitudinal direction. When all 3 translational coordinates were analyzed, a mean composite displacement vector of 8.2 {+-} 2.0 mm (range 4.1-11.7 mm) was obtained for all patients. Based on the findings, image-guided SBRT using the Body Pro-Lok{sup TM} system in conjunction with the MVCT of TomoTherapy is capable of minimizing interfractional setup error and improving treatment accuracy.
- OSTI ID:
- 21486899
- Journal Information:
- Medical Dosimetry, Vol. 36, Issue 2; Other Information: DOI: 10.1016/j.meddos.2010.02.003; PII: S0958-3947(10)00020-8; Copyright (c) 2011 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; ISSN 0958-3947
- Country of Publication:
- United States
- Language:
- English
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