Shadow noise in OCT images of biological tissues

Journal Article · Mon Jun 30 04:00:00 EDT 2008 · Quantum Electronics (Woodbury, N.Y.)

DOI:https://doi.org/10.1070/QE2008V038N06ABEH013839· OSTI ID:21466872

Dolin, L S; Sergeeva, E A; Turchin, I V ^[1]

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1. Institute of Applied Physics, Russian Academy of Sciences, Nizhnii Novgorod (Russian Federation)

Optical coherence tomography (OCT) images of turbid medium with spatially fluctuating optical parameters demonstrate the presence of spatial noise ('shadow noise') caused by shading of the observed layer by variations in scattering and absorption coefficients of superficial layers. In this paper we report the development of the theoretical model of shadow noise in OCT images in which the features for discriminating this type of noise from the noise of a different origin are determined. Shadow noise is discovered in OCT images of biological tissue after specific image processing and the validity of the developed theoretical model is proven. The role of shadow noise as an interfering factor at imaging the variations in the backscattering coefficient, as well as the source of extra information on optical characteristics of the medium is analysed. (special issue devoted to application of laser technologies in biophotonics and biomedical studies)

• OSTI ID: 21466872
• Journal Information: Quantum Electronics (Woodbury, N.Y.), Journal Name: Quantum Electronics (Woodbury, N.Y.) Journal Issue: 6 Vol. 38; ISSN 1063-7818
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
ABSORPTION
ANIMAL TISSUES
BACKSCATTERING
BODY
DIAGNOSTIC TECHNIQUES
IMAGE PROCESSING
IMAGES
LASERS
LAYERS
NOISE
PROCESSING
SCATTERING
SORPTION
TOMOGRAPHY
VARIATIONS