Continuous Intra-Arterial Nimodipine for the Treatment of Cerebral Vasospasm

Journal Article · Sat Nov 15 04:00:00 EST 2008 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-008-9346-0· OSTI ID:21426344

Dichgans, Martin; Straube, Andreas; Birnbaum, Tobias ^[1]; Mueller-Schunk, Stephanie ^[2]; Hamann, Gerhard F ^[3]; Schulte-Altedorneburg, Gernot ^[4]

---

1. University of Munich (LMU), Department of Neurology, Klinikum Grosshadern (Germany)
2. University of Munich (LMU), Department of Neuroradiology, Klinikum Grosshadern (Germany)
3. Dr. Horst Schmidt Klinik, Wiesbaden, Department of Neurology (Germany)
4. University Hospital, Department of Radiology (Germany)

Two patients with refractory symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) were treated by continuous intra-arterial nimodipine infusion via a catheter placed in the internal carotid artery or vertebral artery for 3 and 12 days, respectively. Recovery of the neurological deficits, normalization of MR perfusion, a decrease in the elevated mean flow velocity measured by transcranial duplex sonography, and angiographic recanalization were observed. Continuous intra-arterial nimodipine might be a treatment option in severe refractory vasospasm following SAH.

• OSTI ID: 21426344
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 6 Vol. 31; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BLOOD VESSELS
BODY
BRAIN
CARDIOVASCULAR SYSTEM
CAROTID ARTERIES
CENTRAL NERVOUS SYSTEM
INFUSION
INTAKE
NERVOUS SYSTEM
ORGANS
TUBES