In Vivo Dosimetry With a Linear MOSFET Array to Evaluate the Urethra Dose During Permanent Implant Brachytherapy Using Iodine-125

Journal Article · Sun Nov 15 04:00:00 EST 2009 · International Journal of Radiation Oncology, Biology and Physics

DOI:https://doi.org/10.1016/j.ijrobp.2009.04.042· OSTI ID:21367531

Haanstra, Bjoerk K.C.; Murrer, Lars H.P.; Mijnheer, Ben J; Lambin, Philippe ^[1]

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1. Department of Radiation Oncology (MAASTRO), GROW, University Hospital Maastricht (Netherlands)

Purpose: To develop a technique to monitor the dose rate in the urethra during permanent implant brachytherapy using a linear MOSFET array, with sufficient accuracy and without significantly extending the implantation time. Methods and Materials: Phantom measurements were performed to determine the optimal conditions for clinical measurements. In vivo measurements were performed in 5 patients during the {sup 125}I brachytherapy implant procedure. To evaluate if the urethra dose obtained in the operating room with the ultrasound transducer in the rectum and the patient in treatment position is a reference for the total accumulated dose; additional measurements were performed after the implantation procedure, in the recovery room. Results: In vivo measurements during and after the implantation procedure agree very well, illustrating that the ultrasound transducer in the rectum and patient positioning do not influence the measured dose in the urethra. In vivo dose values obtained during the implantation are therefore representative for the total accumulated dose in the urethra. In 5 patients, the dose rates during and after the implantation were below the maximum dose rate of the urethra, using the planned seed distribution. Conclusion: In vivo dosimetry during the implantation, using a MOSFET array, is a feasible technique to evaluate the dose in the urethra during the implantation of {sup 125}I seeds for prostate brachytherapy.

• OSTI ID: 21367531
• Journal Information: International Journal of Radiation Oncology, Biology and Physics, Journal Name: International Journal of Radiation Oncology, Biology and Physics Journal Issue: 4 Vol. 75; ISSN IOBPD3; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
BRACHYTHERAPY
DAYS LIVING RADIOISOTOPES
DOSE RATES
DOSIMETRY
ELECTRON CAPTURE RADIOISOTOPES
FIELD EFFECT TRANSISTORS
GLANDS
IMPLANTS
IN VIVO
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE 125
IODINE ISOTOPES
ISOTOPES
MALE GENITALS
MEDICINE
MOS TRANSISTORS
MOSFET
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROSTATE
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SEMICONDUCTOR DEVICES
THERAPY
TRANSISTORS
URINARY TRACT