Medical Imaging of Hyperpolarized Gases

Journal Article · Tue Aug 04 00:00:00 EDT 2009 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3215789· OSTI ID:21344472

Miller, G Wilson ^[1]

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1. Radiology Department, University of Virginia, Box 801339, Charlottesville, VA 22908 (United States)

Since the introduction of hyperpolarized {sup 3}He and {sup 129}Xe as gaseous MRI contrast agents more than a decade ago, a rich variety of imaging techniques and medical applications have been developed. Magnetic resonance imaging of the inhaled gas depicts ventilated lung airspaces with unprecedented detail, and allows one to track airflow and pulmonary mechanics during respiration. Information about lung structure and function can also be obtained using the physical properties of the gas, including spin relaxation in the presence of oxygen, restricted diffusion inside the alveolar airspaces, and the NMR frequency shift of xenon dissolved in blood and tissue.

• OSTI ID: 21344472
• Journal Information: AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 1149; ISSN APCPCS; ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANGULAR MOMENTUM
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CONTRAST MEDIA
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DIFFUSION
ELEMENTS
EVEN-ODD NUCLEI
HELIUM 3
HELIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
LUNGS
MAGNETIC RESONANCE
MATERIALS
NMR IMAGING
NONMETALS
NUCLEAR MAGNETIC RESONANCE
NUCLEI
ORGANS
OXYGEN
PARTICLE PROPERTIES
POLARIZATION
RADIOISOTOPES
RELAXATION
RESONANCE
RESPIRATION
RESPIRATORY SYSTEM
SPIN
STABLE ISOTOPES
USES
XENON 129
XENON ISOTOPES