Progress in Development of HIFU CMUTs for use under MR-guidance

Journal Article · Tue Apr 14 04:00:00 EDT 2009 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3131441· OSTI ID:21293559

Wong, Serena H; Kupnik, Mario; Khuri-Yakub, B T ^[1]; Watkins, Ronald D; Pauly, Kim Butts ^[2]

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1. Department of Electrical Engineering, Ginzton Laboratories, Stanford University 450 Via Palou, Stanford, CA 94305 (United States)
2. Department of Radiology, Lucas Center, Stanford University 450 Via Palou, Stanford, CA 94305 (United States)

High intensity focused ultrasound (HIFU) guided by magnetic resonance imaging (MRI) is a noninvasive treatment that potentially reduces patient morbidity, lowers costs, and increases treatment accessibility. Traditionally, piezoelectric transducers are used for HIFU, but capacitive micromachined ultrasonic transducers (CMUTs) have many advantages, including fabrication flexibility, low loss, and efficient transmission. We designed, fabricated, and tested HIFU CMUTs for use under MRI guidance and have demonstrated continuous wave (CW) focusing. In this paper, we demonstrate that CMUTs can be designed for therapeutic ultrasound. First, we demonstrate successful unfocused heating of a HIFU phantom to 18.6 deg. C, which was successfully monitored under MR guidance. Second, we demonstrated a focused CMUT array whose beam profile matched with simulation. In the future, we will expand the array and system for upper abdominal cancer therapy.

• OSTI ID: 21293559
• Journal Information: AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 1113; ISSN 0094-243X; ISSN APCPCS
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BEAM PROFILES
CAVITATION
DISEASE INCIDENCE
FABRICATION
FOCUSING
HEATING
NEOPLASMS
NMR IMAGING
PATIENTS
PHANTOMS
PIEZOELECTRICITY
RADIOTHERAPY
SIMULATION
TRANSDUCERS
ULTRASONIC WAVES