Topical tar: Back to the future

Journal Article · Sat Aug 15 04:00:00 EDT 2009 · Journal of the American Academy of Dermatology

DOI:https://doi.org/10.1016/j.jaad.2008.11.024· OSTI ID:21222437

Paghdal, K V; Schwartz, R A ^[1]

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1. University of Medicine & Dentistry of New Jersey, Newark, NJ (United States)

The use of medicinal tar for dermatologic disorders dates back to the ancient times. Although coal tar is utilized more frequently in modern dermatology, wood tars have also been widely employed. Tar is used mainly in the treatment of chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis, either alone or in combination therapy with other medications, phototherapy, or both. Many modifications have been made to tar preparations to increase their acceptability, as some dislike its odor, messy application, and staining of clothing. One should consider a tried and true treatment with tar that has led to clearing of lesions and prolonged remission times. Occupational studies have demonstrated the carcinogenicity of tar; however, epidemiologic studies do not confirm similar outcomes when used topically. This article will review the pharmacology, formulations, efficacy, and adverse effects of crude coal tar and other tars in the treatment of selected dermatologic conditions.

• OSTI ID: 21222437
• Journal Information: Journal of the American Academy of Dermatology, Journal Name: Journal of the American Academy of Dermatology Journal Issue: 2 Vol. 61; ISSN JAADDB; ISSN 0190-9622
• Country of Publication: United States
• Language: English

Related Subjects

01 COAL, LIGNITE, AND PEAT
COAL TAR
OINTMENTS
REVIEWS
SKIN DISEASES
TAR
THERAPY
WOOD