Tumor therapy with heavy charged particles

Journal Article · Tue Nov 16 04:00:00 EST 1999 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.1301839· OSTI ID:21207602

Blattmann, Hans ^[1]

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1. Division of Radiation Medicine, Paul Scherrer Institute, 5232 Villigen PSI (Switzerland)

Nuclear science has contributed significantly to the development of tumor therapy with heavy charged particles. Interest evolved for neutron therapies in the forties because of the increased radiobiological effectiveness (RBE) compared to photon irradiation. The development of more powerful proton and heavy ion accelerators with higher energies or higher intensities, made new particles for radiation therapy available. Pions, protons, light ions, from helium up to silicon were studied in view of precision dose delivery and increased RBE. Without the parallel development of new diagnostic techniques such as computer tomography (CT) and positron emission tomography (PET) the rapid development would not have been possible. Heavy-charged particle therapy has now come into a consolidation phase. Hospital-based facilities are built by industry, and research institutes focus on refinements in dose delivery and treatment planning, as well as systems for monitoring dose delivery and for dose distribution verification.

• OSTI ID: 21207602
• Journal Information: AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 495; ISSN APCPCS; ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

43 PARTICLE ACCELERATORS
ACCURACY
BEAM MONITORING
BEAM TRANSPORT
DELIVERY
DOSES
HEAVY ION ACCELERATORS
HOSPITALS
ION BEAMS
IRRADIATION
LIGHT IONS
NEOPLASMS
NEUTRON THERAPY
POSITRON COMPUTED TOMOGRAPHY
PROTON BEAMS
RADIATION DOSE DISTRIBUTIONS
RBE