Interpretation of biomonitoring data in clinical medicine and the exposure sciences

Journal Article · Sat Nov 15 00:00:00 EST 2008 · Toxicology and Applied Pharmacology

DOI:https://doi.org/10.1016/j.taap.2008.05.002· OSTI ID:21180471

Barr, Dana B ^[1]; Wright, J Michael ^[2]; Buckley, Brian ^[3]; Magsumbol, Melina S ^[4]

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1. Centers for Disease Control and Prevention (CDC), National Center for Environmental Health, Division of Laboratory Sciences, Atlanta, GA (United States)
2. Environmental Protection Agency, National Center for Environmental Assessment, Cincinnati, OH (United States)
3. Rutgers University, Environmental Occupational Health Sciences Institute, Piscataway, NJ (United States)
4. University of Tennessee Health Science Center, Department of Pediatrics, Memphis, TN (United States)

Biomonitoring has become a fundamental tool in both exposure science and clinical medicine. Despite significant analytical advances, the clinical use of environmental biomarkers remains in its infancy. Clinical use of environmental biomarkers poses some complex scientific and ethical challenges. The purpose of this paper is compare how the clinical and exposure sciences differ with respect to their interpretation and use of biological data. Additionally, the clinical use of environmental biomonitoring data is discussed. A case study is used to illustrate the complexities of conducting biomonitoring research on highly vulnerable populations in a clinical setting.

• OSTI ID: 21180471
• Journal Information: Toxicology and Applied Pharmacology, Vol. 233, Issue 1; Conference: 2007 TRAC: 2007 toxicology and risk assessment conference: Emerging issues and challenges in risk assessment, West Chester, OH (United States), 23-26 Apr 2007; Other Information: DOI: 10.1016/j.taap.2008.05.002; PII: S0041-008X(08)00201-9; Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0041-008X
• Country of Publication: United States
• Language: English

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