The effect of urinary cadmium on cardiovascular fitness as measured by VO{sub 2} max in white, black and Mexican Americans
- Institute of Public Health, Georgia State University, Atlanta, GA (United States)
- School of Health Professions, College of Health and Human Sciences, Georgia State University, Atlanta, GA (United States)
Objectives: We explored potential effects of cadmium exposure on cardiovascular fitness measures, including gender and racial/ethnic differences. Methods: Data were from the 1999 to 2000 National Health and Nutrition Examination Survey (NHANES); 1963 participating subjects were included in our analysis. Volume of oxygen consumed at sub-maximum activity (VO{sub 2} max) were recorded in a series of graded exercises; the goal was to elicit 75% of predetermined age-specific heart rates. Cadmium from urine samples was measured in the laboratory using standard methods. Multivariate linear regression analyses were performed to determine potential relationships. Results: Increased urinary cadmium concentrations were generally associated with decreased estimated VO{sub 2} max values. Gender and racial/ethnic differences were also observed. Specifically, associations were statistically significant for white males and Mexican American females. Conclusion: Inverse associations between urinary cadmium concentrations and estimated VO{sub 2} max values were observed, including racial and gender differences. The implications of such gender and racial/ethnic differences on long-term cardiovascular health and health disparities of present public health concern warrant further investigation.
- OSTI ID:
- 21176125
- Journal Information:
- Environmental Research, Vol. 109, Issue 3; Other Information: DOI: 10.1016/j.envres.2008.11.010; PII: S0013-9351(08)00248-X; Copyright (c) 2008 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved; Country of input: International Atomic Energy Agency (IAEA); ISSN 0013-9351
- Country of Publication:
- United States
- Language:
- English
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