Experiences in US-Guided Percutaneous Radiofrequency Ablation of 44 Renal Tumors in 31 Patients: Analysis of Predictors for Complications and Technical Success

Journal Article · Sun Oct 15 00:00:00 EDT 2006 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-005-0261-3· OSTI ID:21091134

Veltri, Andrea; Calvo, Amedeo; Tosetti, Irene ^[1]; Pagano, Eva ^[2]; Genovesio, Andrea; Virzi, Valentina ^[1]; Ferrando, Ugo ^[3]; Fontana, Dario ^[4]; Gandini, Giovanni ^[1]

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1. University of Turin, Institute of Diagnostic and Interventional Radiology (Italy)
2. University of Turin, Unit of Cancer Epidemiology (Italy)
3. San Giovanni Battista Hospital, Unit of Urology (Italy)
4. University of Turin, Institute of Urology (Italy)

Purpose. Preliminary clinical studies have shown the feasibility, safety, and efficacy of radiofrequency thermal ablation (RFA) of renal tumors, but only a few have analyzed the prognostic factors for technical success and there are no long-term results. Our objective was to statistically evaluate our mid-term results of percutaneous US-guided RFA in order to define predictors for complications and technical success. Methods. We selected for treatment 44 tumors in 31 patients (24 with renal cell carcinoma, 7 with hereditary tumors, 15 with a solitary kidney), up to 5 cm in diameter. Results. Eight adverse events occurred; 3 (6.8%) were major complications, successfully treated with interventional radiology procedures in 2 cases. Exophytic extension of the tumor was protective against complications (p 0.040). Technical success was obtained in 38 lesions after one RFA session and in 39 (89%) after one more session, when possible. At the end of treatment, central extension was the only negative predictor for technical success (p = 0.007), while neither size >3 cm (p = 0.091) nor other prognostic factors were statistically significant. Conclusion. US-guided percutaneous RFA can be proposed for non-central renal tumors up to 5 cm, also in patients without surgical contraindications, thanks to a low incidence of complications and a high success rate. Randomized controlled trials versus surgery are now needed to investigate long-term comparative results.

• OSTI ID: 21091134
• Journal Information: Cardiovascular and Interventional Radiology, Vol. 29, Issue 5; Other Information: DOI: 10.1007/s00270-005-0261-3; Copyright (c) 2006 Springer Science+Business Media, Inc.; www.springer-ny.com; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ABLATION
BIOMEDICAL RADIOGRAPHY
CARCINOMAS
KIDNEYS
PATIENTS
RADIOWAVE RADIATION
SURGERY