Percutaneous CT-Guided Biopsy of the Lung: Comparison Between Aspiration and Automated Cutting Needles Using a Coaxial Technique

Journal Article · Sat Jul 15 04:00:00 EDT 2000 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S002700010067· OSTI ID:21083629

Laurent, Francois; Latrabe, Valerie ^[1]; Vergier, Beatrice ^[2]; Michel, Philippe ^[3]

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1. Imagerie Medicale Radiologie Diagnostique et Therapeutique, Hopital Haut-Leveque, Universite de Bordeaux 2, Avenue de Magellan, F-33604 Pessac (France)
2. Anatomie pathologique, Hopital Haut-Leveque, Universite de Bordeaux 2, Avenue de Magellan, F-33604 Pessac (France)
3. Informatique et Biostatistique, Hopital Haut-Leveque, Avenue de Magellan, F-33604 Pessac (France)

Purpose: To compare the accuracy and complication rate of two different CT-guided transthoracic needle biopsy techniques: fine needle aspiration and an automated biopsy device.Methods: Two consecutive series of respectively 125 (group A) and 98 (group B) biopsies performed using 20-22 gauge coaxial fine needle aspiration (group A) and an automated 19.5 gauge coaxial biopsy device (group B) were compared in terms of their accuracy and complication rate.Results: Groups A and B included respectively 100 (80%) and 77 (79%) malignant lesions and 25 (20%) and 18 (21%) benign lesions. No significant difference was found between the two series concerning patients, lesions, and procedural variables. For a diagnosis of malignancy, a statistically significant difference in sensitivity was found (82.7% vs 97.4%) between results obtained with the automated biopsy device and fine needle aspiration respectively. For a diagnosis of malignancy, the false negative rate of the biopsy result was significantly higher (p <0.005) in group A (17%) than in group B (2.6%). For a specific diagnosis of benignity, no statistically significant difference was found between the two groups (44% vs 26%) but the automated biopsy device provided fewer indeterminate cases. There was no difference between the two groups concerning the pneumothorax rate, which was 20% in group A and 15% in group B, or the hemoptysis rate, which was 2.4% in group A and 4% in group B.Conclusion: For a diagnosis of malignancy when a cytopathologist is not available on-site, automated biopsy devices provide a lower rate of false negative results and a similar complication rate to fine needle aspiration.

• OSTI ID: 21083629
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 4 Vol. 23; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ACCURACY
BIOPSY
CUTTING
DIAGNOSIS
LUNGS
NEOPLASMS
PATIENTS
SENSITIVITY