The Optimal Dose of Nicardipine for Enhancement of Indirect Portography
- Department of Radiology, Minoo City Hospital, 5-7-1 Kayano, Minoo, Osaka 562 (Japan)
- Department of Radiology, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565 (Japan)
- Department of Medicine, Nishiyodo Hospital, 3-5-22 Nosato, Nishiyodogawa-ku, Osaka 555 (Japan)
Purpose: To determine the optimal dose of nicardipine (NCR) for enhancement of indirect portography. Methods: Forty-eight patients underwent conventional film indirect portography via the superior mesenteric artery (SMA) first without and then with preinjection of 1/64-2 mg of NCR into the SMA. Results: NCR (1/8-2 mg) shortened the arterial phase to 50% and the portal appearance time to 60% of control without reflux of contrast medium into the aorta. Portal enhancement was excellent at doses of 1/32 mg or more. Blood pressures and pulse rate showed no significant change at 1/4 mg or less. Conclusion: NCR (1/8-1/4 mg) into the SMA is the optimal dose for achieving sufficient contrast enhancement on indirect portography while reducing the transit time of contrast medium and minimizing effects on the systemic circulation.
- OSTI ID:
- 21080451
- Journal Information:
- Cardiovascular and Interventional Radiology, Vol. 21, Issue 1; Other Information: DOI: 10.1007/s002709900204; Copyright (c) 1998 Springer-Verlag New York Inc; Country of input: International Atomic Energy Agency (IAEA); ISSN 0174-1551
- Country of Publication:
- United States
- Language:
- English
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