Polyurethane-Coated Dacron-Covered Stent-Grafts for TIPS: Results in Swine
Journal Article
·
· Cardiovascular and Interventional Radiology
- Dotter Interventional Institute, Oregon Health Sciences University, L342, 3181 S. W. Sam Jackson Park Road, Portland, OR, 97201 (United States)
- Department of Radiology, University Hospital, Hradec Kralove, PSC 50026 (Czech Republic)
- Department of Radiology, Osaka City University Medical School, 1-5-7, Asahi-Machi, Abeko-Ku, Osaka, 545 (Japan)
- Department of Pathology, Oregon Health Sciences University, 3181 S. W. Sam Jackson Park Road, Portland, OR, 97201 (United States)
Purpose: To evaluate shunt patency after placing a new polyurethane-coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stent-grafts do not improve TIPS patency.
- OSTI ID:
- 21080358
- Journal Information:
- Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 6 Vol. 21; ISSN 0174-1551; ISSN CAIRDG
- Country of Publication:
- United States
- Language:
- English
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