Treatment of hepatocellular carcinoma: A single-center experience

Journal Article · Wed Jan 15 04:00:00 EST 1997 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S002709900104· OSTI ID:21080246

Florio, Francesco; Nardella, Michele; Balzano, Silverio ^[1]; Caturelli, Eugenio; Siena, Domenico ^[2]; Cammisa, Mario ^[1]

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1. IRCCS, Department of Radiology, Hospital 'Casa Sollievo della Sofferenza' (Italy)
2. Hospital 'Casa Sollievo della Sofferenza' IRCCS, Department of Gastroenterology (Italy)

Purpose. The comparative efficacy of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) in the treatment of hepatocellular carcinoma (HCC) was investigated. Methods. Two hundred and sixty consecutive patients were retrospectively analyzed: 156 had received between one and six chemoembolization sessions at 3-month intervals, 33 had had PEI, and the remaining 71 patients refused any treatment. The follow-up ranged from 3 to 36 months. Survival rates were statistically analyzed by life-table analysis. Results. Patients' survival was affected by the number of nodules and by the Child's and Okuda's classes; no relationship was found between survival rates and the histologic grade or vascular supply of the tumor. In the case of a single lesion of Okuda's class I, TACE was more effective than PEI. In multifocal HCC, TACE was better than no treatment in Okuda's class I and Child's class A. Conclusion. We suggest TACE as the treatment of choice in Child A or Okuda I patients with multifocal HCCs; it seems of little help in Child B-C or Okuda II-III patients.

• OSTI ID: 21080246
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 1 Vol. 20; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CHILDREN
ETHANOL
HEPATOMAS
INJECTION
PATIENTS
THERAPY
VASCULAR DISEASES