Two-photon Lee-Goldburg nuclear magnetic resonance: Simultaneous homonuclear decoupling and signal acquisition

Journal Article · Thu Feb 07 04:00:00 EST 2008 · Journal of Chemical Physics

DOI:https://doi.org/10.1063/1.2825593· OSTI ID:21024743

Michal, Carl A; Hastings, Simon P; Lee, Lik Hang ^[1]

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1. Department of Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, British Columbia V6T 1Z1 (Canada)

We present NMR signals from a strongly coupled homonuclear spin system, {sup 1}H nuclei in adamantane, acquired with simultaneous two-photon excitation under conditions of the Lee-Goldburg experiment. Small coils, having inside diameters of 0.36 mm, are used to achieve two-photon nutation frequencies of {approx}20 kHz. The very large rf field strengths required give rise to large Bloch-Siegert shifts that cannot be neglected. These experiments are found to be extremely sensitive to inhomogeneity of the applied rf field, and due to the Bloch-Siegert shift, exhibit a large asymmetry in response between the upper and lower Lee-Goldburg offsets. Two-photon excitation has the potential to enhance both the sensitivity and performance of homonuclear dipolar decoupling, but is made challenging by the high rf power required and the difficulties introduced by the inhomogeneous Bloch-Siegert shift. We briefly discuss a variation of the frequency-switched Lee-Goldburg technique, called four-quadrant Lee-Goldburg (4QLG) that produces net precession in the x-y plane, with a reduced chemical shift scaling factor of 1/3.

• OSTI ID: 21024743
• Journal Information: Journal of Chemical Physics, Journal Name: Journal of Chemical Physics Journal Issue: 5 Vol. 128; ISSN JCPSA6; ISSN 0021-9606
• Country of Publication: United States
• Language: English

Related Subjects

36 MATERIALS SCIENCE
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
CHEMICAL SHIFT
CYCLOALKANES
DECOUPLING
EXCITATION
HYDROGEN 1
KHZ RANGE 01-100
MULTI-PHOTON PROCESSES
NUCLEAR MAGNETIC RESONANCE
PERFORMANCE
PHOTONS
PRECESSION
RADIATION EFFECTS
SENSITIVITY
SIGNALS
SPIN