Dosimetric study and in-vivo dose verification for conformal avoidance treatment of anal adenocarcinoma using helical tomotherapy

Journal Article · Sun Apr 01 04:00:00 EDT 2007 · Medical Dosimetry

OSTI ID:20975199

Chunhui, Han ^[1]; Yijen, Chen ^[2]; An, Liu ^[3]; Schultheiss, Timothy E ^[3]; Wong, Jeffrey Y.C. ^[2]

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1. Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States) and Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States)
2. Division of Radiation Oncology, City of Hope National Medical Center, Duarte, CA (United States)
3. Department of Radiation Physics, City of Hope National Medical Center, Duarte, CA (United States)

This study evaluated the efficacy of using helical tomotherapy for conformal avoidance treatment of anal adenocarcinoma. We retrospectively generated step-and-shoot intensity-modulated radiotherapy (sIMRT) plans and helical tomotherapy plans for two anal cancer patients, one male and one female, who were treated by the sIMRT technique. Dose parameters for the planning target volume (PTV) and the organs-at-risk (OARs) were compared between the sIMRT and the helical tomotherapy plans. The helical tomotherapy plans showed better dose homogeneity in the PTV, better dose conformity around the PTV, and, therefore, better sparing of nearby OARs compared with the sIMRT plans. In-vivo skin dose measurements were performed during conformal avoidance helical tomotherapy treatment of an anal cancer patient to verify adequate delivery of skin dose and sparing of OARs.

• OSTI ID: 20975199
• Journal Information: Medical Dosimetry, Journal Name: Medical Dosimetry Journal Issue: 1 Vol. 32; ISSN 0958-3947; ISSN MEDOEJ
• Country of Publication: United States
• Language: English

Related Subjects

61 RADIATION PROTECTION AND DOSIMETRY
CARCINOMAS
COMPUTERIZED TOMOGRAPHY
DOSIMETRY
IN VIVO
PATIENTS
PLANNING
RADIATION DOSES
RADIOTHERAPY
SKIN
VERIFICATION