Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Scanning electron microscopy of thinned specimens: From multilayers to biological samples

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.2724917· OSTI ID:20960229
; ;  [1]
  1. CNR-IMM, Section of Bologna, via Gobetti 101, Bologna I-40129 (Italy)
The rules governing image formation of thin specimens in scanning and scanning transmission electron microscopy at low energy, deduced from the observation of semiconductor multilayers, were validated on specimens defined by a much more complex structure as the biological ones. It is shown that for a suitable specimen thickness it is possible to have, at the same time, backscattered electron images and scanning transmission electron images with a comparable resolution. Moreover, the nonconductive biological samples can be observed without charging effects if they are thin enough to ensure that a significant fraction of the electron beam crosses the specimen.
OSTI ID:
20960229
Journal Information:
Applied Physics Letters, Journal Name: Applied Physics Letters Journal Issue: 16 Vol. 90; ISSN APPLAB; ISSN 0003-6951
Country of Publication:
United States
Language:
English

Similar Records

A high contrast method of unstained biological samples under a thin carbon film by scanning electron microscopy
Journal Article · Thu Dec 04 23:00:00 EST 2008 · Biochemical and Biophysical Research Communications · OSTI ID:21217121

Contrast and resolution versus specimen thickness in low energy scanning transmission electron microscopy
Journal Article · Fri Jun 01 00:00:00 EDT 2007 · Journal of Applied Physics · OSTI ID:20979430

Spatial Resolution in Scanning Electron Microscopy and Scanning Transmission Electron Microscopy Without a Specimen Vacuum Chamber
Journal Article · Mon Jul 25 00:00:00 EDT 2016 · Microscopy and Microanalysis · OSTI ID:1370449