Three-dimensional time-resolved optical mammography of the uncompressed breast
Optical tomography is being developed as a means of detecting and specifying disease in the adult female breast. We present a series of clinical three-dimensional optical images obtained with a 32-channel time-resolvedsystem and a liquid-coupled interface. Patients place their breasts in a hemispherical cup to whichsources and detectors are coupled, and the remaining space is filled with a highly scattering fluid. Acohort of 38 patients has been scanned, with a variety of benign and malignant lesions. Images show that hypervascularization associated with tumors provides very high contrast due to increased absorption by hemoglobin. Only half of the fibroadenomas scanned could be observed, but of those that could bedetected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation.
- OSTI ID:
- 20929749
- Journal Information:
- Applied Optics, Vol. 46, Issue 17; Other Information: DOI: 10.1364/AO.46.003628; (c) 2007 Optical Society of America; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6935
- Country of Publication:
- United States
- Language:
- English
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