Estimation of radiation dose at various depths for commonly used radionuclides in radiosynoviorthesis in a tissue equivalent material
- Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CT and CRS Building, Anushaktinagar, Mumbai, 400 094 (India)
The purpose of the paper is to report on the dose estimation studies at various depths for the commonly used beta-emitting {sup 90}Y, {sup 166}Ho, {sup 153}Sm, {sup 32}P, and {sup 177}Lu radionuclides in a phantom fabricated using the poly methyl methacrylate tissue equivalent material having a density of 1.19 gm/cc, by using thermoluminescent dosemeters. GAFChromic MD-55 films were used to calculate the calibration factor for the thermoluminescent micro-rods used in our study. It is observed that {sup 90}Y delivers the highest dose at 1 mm amongst the radionuclides tested followed by {sup 32}P, {sup 166}Ho, {sup 153}Sm, and {sup 177}Lu, whereas the cumulative dose received by the joint was found to be more for {sup 32}P followed by {sup 90}Y, {sup 166}Ho, {sup 153}Sm, and {sup 177}Lu. The highest therapeutic range obtained is 3.1 mm for {sup 153}Sm amongst the tested radionuclides. The dose values obtained for all the above-mentioned radionuclides can serve as reference material for those researchers and clinicians who are interested in selection of the radionuclide for the type of joint treated and the amount of dose necessary to be delivered to the synovial membrane.
- OSTI ID:
- 20853373
- Journal Information:
- Medical Physics, Journal Name: Medical Physics Journal Issue: 8 Vol. 33; ISSN 0094-2405; ISSN MPHYA6
- Country of Publication:
- United States
- Language:
- English
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